4.7 Article

TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Subunits of BK channels promote breast cancer development and modulate responses to endocrine treatment in preclinical models

Corinna J. Mohr et al.

Summary: Pore-forming alpha subunits of the BK channel play a role in promoting breast cancer, while the absence or knockdown of BK subunits attenuate the proliferation of breast cancer cells. Tamoxifen stimulates the proliferation of breast cancer cells at low concentrations.

BRITISH JOURNAL OF PHARMACOLOGY (2022)

Review Chemistry, Multidisciplinary

Role of TRPM2 in brain tumours and potential as a drug target

Delphine Ji et al.

Summary: Ion channels, especially TRPM2, play important roles in brain tumours, particularly in relation to oxidative stress and inflammation. Investigating TRPM2 as a potential therapeutic target for brain tumours is of significant interest in the fields of ion channels and pharmacology.

ACTA PHARMACOLOGICA SINICA (2022)

Article Physiology

Large transient capacitive currents in wild-type lysosomal Cl-/H+ antiporter ClC-7 and residual transport activity in the proton glutamate mutant E312A

Michael Pusch et al.

Summary: Research on ClC-7 transporter reveals its dependence on external pH and internal Cl-, while the E312A mutation of the proton glutamate reduces but does not abolish stationary transport currents, potentially explaining the intermediate phenotype observed in the E312A mouse line.

JOURNAL OF GENERAL PHYSIOLOGY (2021)

Review Cell Biology

Band 3 protein function and oxidative stress in erythrocytes

Alessia Remigante et al.

Summary: Band 3 protein (B3p) is an anion transporter that plays a crucial role in erythrocyte homeostasis and cell shape, particularly under oxidative stress conditions. Investigating the functions and anion exchange capability of B3p is significant for understanding related diseases.

JOURNAL OF CELLULAR PHYSIOLOGY (2021)

Review Biochemistry & Molecular Biology

Natural Antioxidants Beneficial Effects on Anion Exchange through Band 3 Protein in Human Erythrocytes

Alessia Remigante et al.

ANTIOXIDANTS (2020)

Article Biochemistry & Molecular Biology

Roles for Ca2+ and K+ channels in cancer cells exposed to the hypoxic tumour microenvironment

Alban Girault et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2020)

Review Pharmacology & Pharmacy

Calcium Permeable Channels in Cancer Hallmarks

Sendoa Tajada et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Pediatrics

Oxidative stress in chronic kidney disease

Kristien Daenen et al.

PEDIATRIC NEPHROLOGY (2019)

Review Biochemistry & Molecular Biology

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

Anju Singh et al.

MOLECULES (2019)

Review Cell Biology

TRPM2 in Cancer

Barbara A. Miller

CELL CALCIUM (2019)

Review Cell Biology

TRP channels in gastric cancer: New hopes and clinical perspectives

Andra M. Sterea et al.

CELL CALCIUM (2019)

Review Cell Biology

Oxidative Stress in Cell Death and Cardiovascular Diseases

Tao Xu et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

Article Multidisciplinary Sciences

Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2

Tabea C. Fricke et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Gastroenterology & Hepatology

Role of ion channels in gastrointestinal cancer

Kyle J. Anderson et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2019)

Article Biochemistry & Molecular Biology

A Role for H2O2 and TRPM2 in the Induction of Cell Death: Studies in KGN Cells

Carsten Theo Hack et al.

ANTIOXIDANTS (2019)

Review Neurosciences

KCa3.1 Channel Modulators as Potential Therapeutic Compounds for Glioblastoma

Brandon M. Brown et al.

CURRENT NEUROPHARMACOLOGY (2018)

Review Neurosciences

K(Ca)3.1 Channels and Glioblastoma: In Vitro Studies

Lukas Klumpp et al.

CURRENT NEUROPHARMACOLOGY (2018)

Article Oncology

TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma

Rui Lin et al.

MOLECULAR MEDICINE REPORTS (2018)

Editorial Material Cell Biology

Oxidative Stress and Membrane Transport Systems

Angela Marino et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

Review Oncology

Oxidation, glycation and glycoxidation-The vicious cycle and lung cancer

Saheem Ahmad et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Cell Biology

ROS signalling in the biology of cancer

Jennifer N. Moloney et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2018)

Review Oncology

Mucosal Melanoma: a Literature Review

Simon Skovsted Yde et al.

CURRENT ONCOLOGY REPORTS (2018)

Article Biochemistry & Molecular Biology

Mechanism of Generation of Oxidative Stress and Pathophysiology of Type 2 Diabetes Mellitus: How Are They Interlinked?

Kanwal Rehman et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2017)

Article Neurosciences

Subunit-dependent oxidative stress sensitivity of LRRC8 volume-regulated anion channels

Antonella Gradogna et al.

JOURNAL OF PHYSIOLOGY-LONDON (2017)

Review Biochemistry & Molecular Biology

Ion channels or aquaporins as novel molecular targets in gastric cancer

Jianling Xia et al.

MOLECULAR CANCER (2017)

Review Physiology

MOLECULAR DETERMINANTS OF BK CHANNEL FUNCTIONAL DIVERSITY AND FUNCTIONING

Ramon Latorre et al.

PHYSIOLOGICAL REVIEWS (2017)

Article Biochemistry & Molecular Biology

Oxidative stress activates the TRPM2-Ca2+-CaMKII-ROS signaling loop to induce cell death in cancer cells

Qian Wang et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)

Review Neurosciences

TRPM2 protects against tissue damage following oxidative stress and ischaemia-reperfusion

Barbara A. Miller et al.

JOURNAL OF PHYSIOLOGY-LONDON (2016)

Review Cell Biology

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

Pierpaola Davalli et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Article Gastroenterology & Hepatology

Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development

Violeta Zuniga-Garcia et al.

DIGESTIVE DISEASES AND SCIENCES (2015)

Review Cell Biology

Cellular Mechanisms of Oxidative Stress and Action in Melanoma

Mario Venza et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)

Review Biochemistry & Molecular Biology

Oxidative stress: a concept in redox biology and medicine

Helmut Sies

REDOX BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Oxidative Stress and Maxi Calcium-Activated Potassium (BK) Channels

Anton Hermann et al.

BIOMOLECULES (2015)

Article Dermatology

Cutaneous Malignant Melanoma: Update on Diagnostic and Prognostic Biomarkers

Ossama Abbas et al.

AMERICAN JOURNAL OF DERMATOPATHOLOGY (2014)

Review Oncology

Oxidative Stress and Antioxidants in Disease and Cancer: A Review

Rakesh Kumar Gupta et al.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2014)

Article Physiology

Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism

Yu Zhou et al.

JOURNAL OF GENERAL PHYSIOLOGY (2014)

Review Physiology

BK channel activators and their therapeutic perspectives

Bo H. Bentzen et al.

FRONTIERS IN PHYSIOLOGY (2014)

Review Oncology

The roles of K+ channels in cancer

Luis A. Pardo et al.

NATURE REVIEWS CANCER (2014)

Review Cell Biology

Oxidative stress and cancer: An overview

Venus Sosa et al.

AGEING RESEARCH REVIEWS (2013)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Review Biotechnology & Applied Microbiology

Modulation of oxidative stress as an anticancer strategy

Chiara Gorrini et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Article Pharmacology & Pharmacy

Effect of non-steroidal anti-inflammatory drugs and new fenamate analogues on TRPC4 and TRPC5 channels

Hongni Jiang et al.

BIOCHEMICAL PHARMACOLOGY (2012)

Article Physiology

Modulation of K2P3.1 (TASK-1), K2P9.1 (TASK-3), and TASK-1/3 heteromer by reactive oxygen species

Justin R. Papreck et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2012)

Article Multidisciplinary Sciences

Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

Makiko Kashio et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Activity of BKCa Channel Is Modulated by Membrane Cholesterol Content and Association with Na+/K+-ATPase in Human Melanoma IGR39 Cells

Nobuyoshi Tajima et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtK(Ca)3.1

Nicola Sassi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)

Article Biochemical Research Methods

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson et al.

BIOINFORMATICS (2010)

Article Biochemistry & Molecular Biology

Biphasic effects of H2O2 on BKCa channels

Bo Liu et al.

FREE RADICAL RESEARCH (2010)

Article Multidisciplinary Sciences

The Regulation of miRNA-211 Expression and Its Role in Melanoma Cell Invasiveness

Joseph Mazar et al.

PLOS ONE (2010)

Article Biotechnology & Applied Microbiology

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead et al.

GENOME BIOLOGY (2009)

Article Oncology

Silencing of hSlo potassium channels in human osteosarcoma cells promotes tumorigenesis

Beatrice Cambien et al.

INTERNATIONAL JOURNAL OF CANCER (2008)

Article Medicine, Research & Experimental

TRPA1 is a major oxidant sensor in murine airway sensory neurons

Bret F. Bessac et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Article Chemistry, Medicinal

Novel inhibitors of the Gardos channel for the treatment of sickle cell disease

Grant A. McNaughton-Smith et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Review Cardiac & Cardiovascular Systems

N-(p-amylcinnamoyl)anthranilic acid (ACA): A phospholipase A(2) inhibitor and TRP channel blocker

Christian Harteneck et al.

CARDIOVASCULAR DRUG REVIEWS (2007)

Article Pharmacology & Pharmacy

Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid

Robert Kraft et al.

BRITISH JOURNAL OF PHARMACOLOGY (2006)

Article Pharmacology & Pharmacy

Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole

K Hill et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)

Article Cell Biology

Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia

R Kraft et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)

Review Physiology

Oxidative regulation of large conductance calcium-activated potassium channels

XD Tang et al.

JOURNAL OF GENERAL PHYSIOLOGY (2001)