Related references
Note: Only part of the references are listed.DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations
Byung Woo Kim et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2020)
Oxygen-Dependent Accumulation of Purine DNA Lesions in Cockayne Syndrome Cells
Marios G. Krokidis et al.
CELLS (2020)
Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling
Mustafa N. Okur et al.
AGING CELL (2020)
Cockayne Syndrome Type A Protein Protects Primary Human Keratinocytes from Senescence
Sonia Cordisco et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2019)
ROS-mediated activation and mitochondrial translocation of CaMKII contributes to Drp1-dependent mitochondrial fission and apoptosis in triple-negative breast cancer cells by isorhamnetin and chloroquine
Jinjiao Hu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Mitochondrial fragmentation and network architecture in degenerative diseases
Syed Shah et al.
PLOS ONE (2019)
Purine DNA Lesions at Different Oxygen Concentration in DNA Repair-Impaired Human Cells (EUE-siXPA)
Marios G. Krokidis et al.
CELLS (2019)
CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence
Clement Crochemore et al.
NATURE COMMUNICATIONS (2019)
Mitochondrial membrane potential
Ljubava D. Zorova et al.
ANALYTICAL BIOCHEMISTRY (2018)
CSA and CSB play a role in the response to DNA breaks
Barbara Pascucci et al.
Oncotarget (2018)
Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome
Marius Costel Alupei et al.
CELL REPORTS (2018)
HDAC inhibition improves autophagic and lysosomal function to prevent loss of subcutaneous fat in a mouse model of Cockayne syndrome
Marc Majora et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells
Barbara Pascucci et al.
ONCOTARGET (2017)
Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model
Wenzhang Wang et al.
HUMAN MOLECULAR GENETICS (2017)
Mdivi-1 Protects Adult Rat Hippocampal Neural Stem Cells against Palmitate-Induced Oxidative Stress and Apoptosis
Sehee Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Mitochondria-Division Inhibitor 1 Protects Against Amyloid-beta induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease
P. Hemachandra Reddy et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species
Evan A. Bordt et al.
DEVELOPMENTAL CELL (2017)
Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options
Wilbert P. Vermeij et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)
A mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmentation and attenuates kainic acid-induced hippocampal cell death
Hwajin Kim et al.
BMC NEUROSCIENCE (2016)
CELL BIOLOGY Form follows function for mitochondria
Chunxin Wang et al.
NATURE (2016)
Mitochondrial division inhibitor 1 protects against mutant huntingtin-induced abnormal mitochondrial dynamics and neuronal damage in Huntington's disease
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2015)
An altered redox balance and increased genetic instability characterize primary fibroblasts derived from xeroderma pigmentosum group A patients
Eleonora Parlanti et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2015)
Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome
Laurent Chatre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo
Xing Guo et al.
BIOCHEMICAL JOURNAL (2014)
Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth
Sylvia Koch et al.
CELL CYCLE (2014)
A High-Fat Diet and NAD+ Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome
Morten Scheibye-Knudsen et al.
CELL METABOLISM (2014)
Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage
James E. Cleaver et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
A selective inhibitor of Drp1, mdivi-1, acts against cerebral ischemia/reperfusion injury via an anti-apoptotic pathway in rats
Ning Zhang et al.
NEUROSCIENCE LETTERS (2013)
Physiological and Pathological Significance of Dynamin-Related Protein 1 (Drp1)-Dependent Mitochondrial Fission in the Nervous System
Bongki Cho et al.
Experimental Neurobiology (2013)
An altered redox balance mediates the hypersensitivity of Cockayne syndrome primary fibroblasts to oxidative stress
Barbara Pascucci et al.
AGING CELL (2012)
Interaction between the Cockayne syndrome B and p53 proteins: implications for aging
Mattia Frontini et al.
AGING-US (2012)
Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease
Ulziibat P. Shirendeb et al.
HUMAN MOLECULAR GENETICS (2012)
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
Morten Scheibye-Knudsen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation
Brian R. Berquist et al.
NUCLEIC ACIDS RESEARCH (2012)
EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines
Sergey I. Dikalov et al.
FREE RADICAL RESEARCH (2011)
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2011)
Mitochondrial dysfunction in Parkinson's disease
Konstanze F. Winklhofer et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane
Maria D. Aamann et al.
FASEB JOURNAL (2010)
Defective repair of 5-hydroxy-2'-deoxycytidine in Cockayne syndrome cells and its complementation by Escherichia coli formamidopyrimidine DNA glycosylase and endonuclease III
Mara Foresta et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging
York Kamenisch et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Accumulation of mitochondrial DNA damage and bioenergetic dysfunction in CSB defective cells
Pia O. Osenbroch et al.
FEBS JOURNAL (2009)
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization
Ann Cassidy-Stone et al.
DEVELOPMENTAL CELL (2008)
The role of CSA in the response to oxidative DNA damage in human cells
M. D'Errico et al.
ONCOGENE (2007)
Muscle fiber-specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction
T Phillips et al.
FASEB JOURNAL (2005)
Mitochondrial fission in apoptosis, neurodegeneration and aging
E Bossy-Wetzel et al.
CURRENT OPINION IN CELL BIOLOGY (2003)
CSB is a component of RNA pol I transcription
J Bradsher et al.
MOLECULAR CELL (2002)
The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA
J Tuo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
S Frank et al.
DEVELOPMENTAL CELL (2001)