Related references
Note: Only part of the references are listed.Human Vγ9Vδ2 T cells exert anti-tumor activity independently of PD-L1 expression in tumor cells
Mako Tomogane et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia
Jamie Y. Story et al.
CYTOTHERAPY (2021)
BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells
Carla E. Cano et al.
CELL REPORTS (2021)
Targeting signalling pathways and the immune microenvironment of cancer stem cells - a clinical update
Joseph A. Clara et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2020)
Fibrosis and cancer: A strained relationship
Bram Piersma et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
Tumor microenvironment complexity and therapeutic implications at a glance
Roghayyeh Baghba et al.
CELL COMMUNICATION AND SIGNALING (2020)
Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing
Mohindar M. Karunakaran et al.
IMMUNITY (2020)
Sphere-derived Prostate Cancer Stem Cells Are Resistant to γδ T Cell Cytotoxicity
Masatsugu Miyashita et al.
ANTICANCER RESEARCH (2020)
Targeting Tumor Microenvironment for Cancer Therapy
Catarina Roma-Rodrigues et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma
Cedric Rossi et al.
ONCOIMMUNOLOGY (2019)
Towards Deciphering the Hidden Mechanisms That Contribute to the Antigenic Activation Process of Human Vγ9Vδ2 T Cells
Lola Boutin et al.
FRONTIERS IN IMMUNOLOGY (2018)
Myeloid-Derived Suppressor Cells Specifically Suppress IFN-γ Production and Antitumor Cytotoxic Activity of Vδ2 T Cells
Alessandra Sacchi et al.
FRONTIERS IN IMMUNOLOGY (2018)
Tribody [(HER2)2xCD16] Is More Effective Than Trastuzumab in Enhancing γδ T Cell and Natural Killer Cell Cytotoxicity Against HER2-Expressing Cancer Cells
Hans H. Oberg et al.
FRONTIERS IN IMMUNOLOGY (2018)
Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression
Viktor Fleming et al.
FRONTIERS IN IMMUNOLOGY (2018)
Low dose gemcitabine increases the cytotoxicity of human Vγ9Vδ2 T cells in bladder cancer cells in vitro and in an orthotopic xenograft model
Teruki Shimizu et al.
ONCOIMMUNOLOGY (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
Immune Checkpoint Inhibitors: Toward New Paradigms in Renal Cell Carcinoma
Ronan Flippot et al.
DRUGS (2018)
Dual role of macrophage in tumor immunity
Ryota Tamura et al.
IMMUNOTHERAPY (2018)
Mevalonate Metabolism in Cancer Stemness and Trained Immunity
Georg Gruenbacher et al.
FRONTIERS IN ONCOLOGY (2018)
CCR5(+) Myeloid-Derived Suppressor Cells Are Enriched and Activated in Melanoma Lesions
Carolin Blattner et al.
CANCER RESEARCH (2018)
Regulatory T cells in cancer immunotherapy
Atsushi Tanaka et al.
CELL RESEARCH (2017)
Avoidance of On-Target Off-Tumor Activation Using a Co-stimulation-Only Chimeric Antigen Receptor
Jonathan Fisher et al.
MOLECULAR THERAPY (2017)
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
Sydney R. Gordon et al.
NATURE (2017)
Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
J. D. Wolchok et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage
Elena Lo Presti et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Entinostat Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma
Ashley Orillion et al.
CLINICAL CANCER RESEARCH (2017)
CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell-Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1
Yunqin Lee et al.
CLINICAL CANCER RESEARCH (2016)
IL17 producing γδT cells induce angiogenesis and are associated with poor survival in gallbladder cancer patients
Rushikesh Sudam Patil et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Isopentenyl pyrophosphate secreted from Zoledronate-stimulated myeloma cells, activates the chemotaxis of γδT cells
Eishi Ashihara et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
γδ T cell activation by bispecific antibodies
Hans-Heinrich Oberg et al.
CELLULAR IMMUNOLOGY (2015)
Activation of Human γδ T Cells by Cytosolic Interactions of BTN3A1 with Soluble Phosphoantigens and the Cytoskeletal Adaptor Periplakin
David A. Rhodes et al.
JOURNAL OF IMMUNOLOGY (2015)
Molecules and mechanisms implicated in the peculiar antigenic activation process of human Vγ9Vδ2T cells
Christelle Harly et al.
FRONTIERS IN IMMUNOLOGY (2015)
Prostate Cancer Stem-like Cells Contribute to the Development of Castration-Resistant Prostate Cancer
Diane Ojo et al.
CANCERS (2015)
γδ T Cell Immunotherapy-A Review
Hirohito Kobayashi et al.
PHARMACEUTICALS (2015)
Antibody-modified T cells: CARs take the front seat for hematologic malignancies
Marcela V. Maus et al.
BLOOD (2014)
Novel Bispecific Antibodies Increase γδ T-Cell Cytotoxicity against Pancreatic Cancer Cells
Hans-Heinrich Oberg et al.
CANCER RESEARCH (2014)
Tumor-Antigen-Binding Bispecific Antibodies for Cancer Treatment
Ulrich H. Weidle et al.
SEMINARS IN ONCOLOGY (2014)
Intraperitoneal injection of in vitro expanded Vγ9Vδ2 T cells together with zoledronate for the treatment of malignant ascites due to gastric cancer
Ikuo Wada et al.
CANCER MEDICINE (2014)
Role of cancer stem cell-associated inflammation in creating pro-inflammatory tumorigenic microenvironments
Masahisa Jinushi
ONCOIMMUNOLOGY (2014)
Anti-tumour immunotherapy with Vγ9Vδ2 T lymphocytes: from the bench to the bedside
Mounia S. Braza et al.
BRITISH JOURNAL OF HAEMATOLOGY (2013)
Chemoimmunotherapy: reengineering tumor immunity
Gang Chen et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Ex vivo characterization of γδ T-cell repertoire in patients after adoptive transfer of Vγ9Vδ2 T cells expressing the interleukin-2 receptor β-chain and the common γ-chain
Takamichi Izumi et al.
CYTOTHERAPY (2013)
Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies
Yannick Bulliard et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma
Tyler R. Simpson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
The functional impairment of HCC-infiltrating γδ T cells, partially mediated by regulatory T cells in a TGFβ- and IL-10-dependent manner
Yong Yi et al.
JOURNAL OF HEPATOLOGY (2013)
Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen Receptor
Drew C. Deniger et al.
MOLECULAR THERAPY (2013)
The activity of γδ T cells against paediatric liver tumour cells and spheroids in cell culture
Alexander Hoh et al.
LIVER INTERNATIONAL (2013)
Safety and Tumor Responses with Lambrolizumab (Anti-PD-1) in Melanoma
Omid Hamid et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Engineered Drug Resistant γδ T Cells Kill Glioblastoma Cell Lines during a Chemotherapy Challenge: A Strategy for Combining Chemo- and Immunotherapy
Lawrence S. Lamb et al.
PLOS ONE (2013)
Chemotherapy Sensitizes Colon Cancer Initiating Cells to Vγ9Vδ2 T Cell- Mediated Cytotoxicity
Matilde Todaro et al.
PLOS ONE (2013)
Tumor stroma as targets for cancer therapy
Jing Zhang et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans
Daisuke Sugiyama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Anti-CTLA-4 Antibodies of IgG2a Isotype Enhance Antitumor Activity through Reduction of Intratumoral Regulatory T Cells
Mark J. Selby et al.
CANCER IMMUNOLOGY RESEARCH (2013)
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
Paolo P. Provenzano et al.
CANCER CELL (2012)
Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO
Tuanjie Li et al.
CANCER LETTERS (2012)
CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Marco Velasco-Velazquez et al.
CANCER RESEARCH (2012)
HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells
Nadire Duru et al.
CLINICAL CANCER RESEARCH (2012)
IL-21 enhances the potential of human γδ T cells to provide B-cell help
Raj R. Bansal et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
Helene Salmon et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Tumor-promoting Versus Tumor-antagonizing Roles of γδ T Cells in Cancer Immunotherapy: Results From a Prospective Phase I/II Trial
Volker Kunzmann et al.
JOURNAL OF IMMUNOTHERAPY (2012)
The blockade of immune checkpoints in cancer immunotherapy
Drew M. Pardoll
NATURE REVIEWS CANCER (2012)
Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 T cells
Nadia Caccamo et al.
BLOOD (2011)
Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours
A. J. Nicol et al.
BRITISH JOURNAL OF CANCER (2011)
Phase I/II study of adoptive transfer of γδ T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma
Hirohito Kobayashi et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
Pilot trial of interleukin-2 and zoledronic acid to augment γδ T cells as treatment for patients with refractory renal cell carcinoma
Joshua M. Lang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
Early Detection of Tumor Cells by Innate Immune Cells Leads to Treg Recruitment through CCL22 Production by Tumor Cells
Julien Faget et al.
CANCER RESEARCH (2011)
Zoledronate-activated V gamma 9 gamma delta T cell-based immunotherapy is feasible and restores the impairment of gamma delta T cells in patients with solid tumors
Atsutaka Noguchi et al.
CYTOTHERAPY (2011)
Expression and function of PD-1 in human γδ T cells that recognize phosphoantigens
Masashi Iwasaki et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2
Yuxian Huang et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2011)
EGFR Inhibitors Enhanced the Susceptibility to NK Cell-mediated Lysis of Lung Cancer Cells
Hyunsu Kim et al.
JOURNAL OF IMMUNOTHERAPY (2011)
Adoptive Immunotherapy for Advanced Non-small Cell Lung Cancer Using Zoledronate-expanded γδ T Cells: A Phase I Clinical Study
Miki Sakamoto et al.
JOURNAL OF IMMUNOTHERAPY (2011)
Preclinical evaluation of ex vivo expanded/activated gamma delta T cells for immunotherapy of glioblastoma multiforme
Nichole L. Bryant et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
Phase I study of bromohydrin pyrophosphate (BrHPP, IPH 1101), a Vγ9Vδ2 T lymphocyte agonist in patients with solid tumors
Jaafar Bennouna et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2010)
Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells
Tobias Schatton et al.
CANCER RESEARCH (2010)
In vivo manipulation of Vγ9Vδ2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients
S. Meraviglia et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients
Tiziano Di Tomaso et al.
CLINICAL CANCER RESEARCH (2010)
TRAIL: A Sword for Killing Tumors
S. Wang
CURRENT MEDICINAL CHEMISTRY (2010)
A phase I study of adoptive immunotherapy for recurrent non-small-cell lung cancer patients with autologous γδ T cells
Jun Nakajima et al.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2010)
Tumor-infiltrating IL-17-producing γδ T cells support the progression of tumor by promoting angiogenesis
Daiko Wakita et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
CD133 expression predicts for non-response to chemotherapy in colorectal cancer
Chee W. Ong et al.
MODERN PATHOLOGY (2010)
Dysregulation of the mevalonate pathway promotes transformation
James W. Clendening et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Peripheral blood monocytes are responsible for gamma delta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP
Anke J. Roelofs et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Intravesical administration of gamma delta T cells successfully prevents the growth of bladder cancer in the murine model
Takeshi Yuasa et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2009)
DNAX accessory molecule-1 (CD226) promotes human hepatocellular carcinoma cell lysis by Vγ9Vδ2 T cells
Olivier Toutirais et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Clinical and immunological evaluation of zoledronate-activated Vγ9γδ T-cell-based immunotherapy for patients with multiple myeloma
Yu Abe et al.
EXPERIMENTAL HEMATOLOGY (2009)
FROUNT Is a Common Regulator of CCR2 and CCR5 Signaling to Control Directional Migration
Etsuko Toda et al.
JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: TGF-β1 and IL-15 Induce FOXP3+ γδ Regulatory T Cells in the Presence of Antigen Stimulation
Rita Casetti et al.
JOURNAL OF IMMUNOLOGY (2009)
Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer
Marcus C. B. Tan et al.
JOURNAL OF IMMUNOLOGY (2009)
Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment
Jonathan M. Weiss et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Immunogenic and tolerogenic cell death
Douglas R. Green et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Phase-I study of Innacell γδ™, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma
Jaafar Bennouna et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
F. Stephen Hodi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
CTLA-4 blockade increases IFNγ-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
Chrysoula I. Liakou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Targeting human γδ T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer
Francesco Dieli et al.
CANCER RESEARCH (2007)
Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associllited T cells
Michael R. Nazareth et al.
JOURNAL OF IMMUNOLOGY (2007)
Distinct cytokine-driven responses of activated blood γδ T cells:: Insights into unconventional T cell pleiotropy
David Vermijlen et al.
JOURNAL OF IMMUNOLOGY (2007)
Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study
Hirohito Kobayashi et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)
γδT cells kill myeloma cells by sensing mevalonate metabolites and ICAM-1 molecules on cell surface
Ryo Uchida et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
Paolo Serafini et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Chemotherapy pretreatment sensitizes solid tumor-derived cell lines to Vα24+ NKT cell-mediated cytotoxicity
Stephen R. Mattarollo et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
The DNA damage response, immunity and cancer
Stephan Gasser et al.
SEMINARS IN CANCER BIOLOGY (2006)
The molecular mechanism of nitrogen-containing bisphosphonates as anti osteoporosis drugs
Kathryn L. Kavanagh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B
S Skov et al.
CANCER RESEARCH (2005)
Vγ9Vδ2 T cell response to colon carcinoma cells
M Corvaisier et al.
JOURNAL OF IMMUNOLOGY (2005)
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
K Ko et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Activation of Vγ9Vδ2 T cells by NKG2D
B Rincon-Orozco et al.
JOURNAL OF IMMUNOLOGY (2005)
Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis
Y Terashima et al.
NATURE IMMUNOLOGY (2005)
Ex vivo expanded human Vγ9Vδ2+γδ-T cells mediate innate antitumor activity against human prostate cancer cells in vitro
ZY Liu et al.
JOURNAL OF UROLOGY (2005)
Phosphostim-activated γδ T cells kill autologous metastatic renal cell carcinoma
E Viey et al.
JOURNAL OF IMMUNOLOGY (2005)
Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo
S Shankar et al.
PROSTATE (2005)
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
TJ Curiel et al.
NATURE MEDICINE (2004)
Induction of γδ T-lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo
F Dieli et al.
BLOOD (2003)
γδ T cells for immune therapy of patients with lymphoid malignancies
M Wilhelm et al.
BLOOD (2003)
ULBP4 is a novel ligand for human NKG2D
NJ Chalupny et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Human T cell receptor γδ cells recognize endogenous mevalonate metabolites in tumor cells
HJ Gober et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human γδ T cells in Escherichia coli
M Hintz et al.
FEBS LETTERS (2001)
Differentiation of resting human peripheral blood γδ T cells toward Th1-or Th2-phenotype
D Wesch et al.
CELLULAR IMMUNOLOGY (2001)
MICA engagement by human Vγ2Vδ2 T cells enhances their antigen-dependent effector function
H Das et al.
IMMUNITY (2001)
ULBPs, novel MHC class I-related molecules bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
D Cosman et al.
IMMUNITY (2001)
Share Paper
