Anti-Pigmentary Natural Compounds and Their Mode of Action

Hyper-activated melanocytes are the major cause of skin hyper-pigmentary disorders, such as freckles and melasma. Increasing efforts have been made to search for materials with depigmenting activity to develop functional cosmetics. As a result, numerous materials have been reported to have depigmenting activity but some of them are known to cause unwanted side effects. Consequently, anti-pigmentary natural compounds without concern of toxicity are in great demand. Virtually all sorts of natural sources have been investigated to find anti-pigmentary natural compounds. This review summarizes recently reported anti-pigmentary natural compounds and their mode of action from the ocean, plants, and bacteria.

Automated summary

Hyper-activated melanocytes are the main cause of skin hyper-pigmentary disorders, leading to a high demand for anti-pigmentary natural compounds without toxicity concerns. Research has focused on finding such compounds from various natural sources, including the ocean, plants, and bacteria.