Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/ijms22115539
Keywords
migraine; sleep; sleep disorders; serotonin; melatonin; orexins; dopamine
Funding
- Wroclaw Medical University [SUB.C.220.21.028]
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Migraine and sleep disorders are common chronic diseases with significant negative impacts on society and economy. The association between them is observed but not fully understood, with recent progress in understanding common anatomical structures and pathogenetic mechanisms. Better understanding of these mechanisms in the future will expand treatment options.
Migraine and sleep disorders are common chronic diseases in the general population, with significant negative social and economic impacts. The association between both of these phenomena has been observed by clinicians for years and is confirmed by many epidemiological studies. Despite this, the nature of this relationship is still not fully understood. In recent years, there has been rapid progress in understanding the common anatomical structures of and pathogenetic mechanism between sleep and migraine. Based on a literature review, the authors present the current view on this topic as well as ongoing research in this field, with reference to the key points of the biochemical and neurophysiological processes responsible for both these disorders. In the future, a better understanding of these mechanisms will significantly expand the range of treatment options.
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