4.7 Article

Norepinephrine Protects against Methamphetamine Toxicity through β2-Adrenergic Receptors Promoting LC3 Compartmentalization

Related references

Note: Only part of the references are listed.
Review Behavioral Sciences

Autophagy status as a gateway for stress-induced catecholamine interplay in neurodegeneration

Francesco Fornai et al.

Summary: The catecholamine-containing brainstem nuclei LC and VTA are crucial for stress responses and may contribute to neurodegeneration, especially during chronic stress. Alterations in catecholamine systems can lead to cognitive decline and potentially increase the production of toxic dopamine and norepinephrine by-products, affecting proteostasis in various brain regions. The molecular events controlling neurotransmission, neuroplasticity, and proteostasis within LC and VTA impact different brain areas, with alterations in autophagy machinery within these nuclei potentially triggering early neurodegeneration.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2021)

Review Biochemistry & Molecular Biology

Autophagy and the Wnt signaling pathway: A focus on Wnt/β-catenin signaling

Shahrokh Lorzadeh et al.

Summary: The interplay between autophagy and Wnt signaling pathways is crucial for regulating cellular homeostasis and adaptation to environmental conditions. Autophagy degrades and recycles cellular materials, while Wnt signaling is involved in embryogenesis and differentiation.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2021)

Article Cell Biology

Biased agonism at β-adrenergic receptors

Michael Ippolito et al.

Summary: β-adrenergic receptors consist of three subtypes and play important roles in regulating physiological processes. Developing biased agonists could potentially enhance treatment efficacy for diseases.

CELLULAR SIGNALLING (2021)

Article Biochemistry & Molecular Biology

Neuroprotective Effects of Curcumin in Methamphetamine-Induced Toxicity

Larisa Ryskalin et al.

Summary: Curcumin, a natural polyphenol extracted from Curcuma longa L, has potential health benefits including activation of autophagy and protection against toxic substances like METH. This study demonstrates that Curcumin counteracts METH toxicity by promoting autophagy, leading to clearance of harmful substances like alpha-synuclein in cells.

MOLECULES (2021)

Review Cell Biology

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky et al.

Summary: The guidelines presented in this article aim to assist researchers in selecting and interpreting methods to examine autophagy, as well as to help reviewers provide constructive critiques of reports focused on these processes. It emphasizes that no single assay is perfect for every situation, and multiple techniques may be needed to properly monitor autophagy in different experimental settings. The article also highlights the importance of targeting multiple autophagy-related genes in genetic approaches to block autophagy effectively.

AUTOPHAGY (2021)

Review Clinical Neurology

Central Noradrenergic Agonists in the Treatment of Ischemic Stroke-an Overview

Zohi Sternberg et al.

TRANSLATIONAL STROKE RESEARCH (2020)

Article Multidisciplinary Sciences

β-Arrestin2 oligomers impair the clearance of pathological tau and increase tau aggregates

Jung-A A. Woo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Neurosciences

Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease

David Weinshenker

TRENDS IN NEUROSCIENCES (2018)

Article Cell Biology

mTOR Modulates Methamphetamine-Induced Toxicity through Cell Clearing Systems

Gloria Lazzeri et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

Article Biochemistry & Molecular Biology

The ChEMBL database in 2017

Anna Gaulton et al.

NUCLEIC ACIDS RESEARCH (2017)

Review Anatomy & Morphology

The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer's Disease

Filippo S. Giorgi et al.

FRONTIERS IN NEUROANATOMY (2017)

Article Anatomy & Morphology

Systematic Morphometry of Catecholamine Nuclei in the Brainstem.

Domenico Bucci et al.

FRONTIERS IN NEUROANATOMY (2017)

Article Neurosciences

Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease

Sarah C. Kelly et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)

Article Neurosciences

Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin

Cinzia Fabrizi et al.

NEUROTOXICOLOGY (2016)

Article Anatomy & Morphology

The Autophagoproteasome a Novel Cell Clearing Organelle in Baseline and Stimulated Conditions

Paola Lenzi et al.

FRONTIERS IN NEUROANATOMY (2016)

Article Multidisciplinary Sciences

Neurotransmitter and psychostimulant recognition by the dopamine transporter

Kevin H. Wang et al.

NATURE (2015)

Article Cardiac & Cardiovascular Systems

Cardiac sympathetic neurons provide trophic signal to the heart via 2-adrenoceptor-dependent regulation of proteolysis

Tania Zaglia et al.

CARDIOVASCULAR RESEARCH (2013)

Article Pharmacology & Pharmacy

The Effects of Locus Coeruleus and Norepinephrine in Methamphetamine Toxicity

Michela Ferrucci et al.

Current Neuropharmacology (2013)

Article Biochemistry & Molecular Biology

Beta(2)-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation

Pablo Aranguiz-Urroz et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)

Article Behavioral Sciences

Autoradiographic study of serotonin transporter during memory formation

Ruth Tellez et al.

BEHAVIOURAL BRAIN RESEARCH (2010)

Article Pharmacology & Pharmacy

The selectivity of β-adrenoceptor agonists at human β1-, β2- and β3-adrenoceptors

Jillian G. Baker

BRITISH JOURNAL OF PHARMACOLOGY (2010)

Article Biochemistry & Molecular Biology

Changes and role of adrenoceptors in PC12 cells after phenylephrine administration and apoptosis induction

Lubomira Lencesova et al.

NEUROCHEMISTRY INTERNATIONAL (2010)

Article Neurosciences

The discovery of central monoamine neurons gave volume transmission to the wired brain

Kjell Fuxe et al.

PROGRESS IN NEUROBIOLOGY (2010)

Article Cell Biology

Autophagy for the avoidance of neurodegeneration

Frank Madeo et al.

GENES & DEVELOPMENT (2009)

Article Multidisciplinary Sciences

Role of Autophagy during Methamphetamine Neurotoxicity

Livia Pasquali et al.

DRUG ADDICTION: RESEARCH FRONTIERS AND TREATMENT ADVANCES (2008)

Article Biochemistry & Molecular Biology

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

Roberta Castino et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Review Biochemistry & Molecular Biology

The role of the plasmalemmal dopamine and vesicular monoamine transporters in methamphetamine-induced dopaminergic deficits

Trent J. Volz et al.

JOURNAL OF NEUROCHEMISTRY (2007)

Article Chemistry, Medicinal

Role of Tyr356(7.43) and Ser190(4.57) in antagonist binding in the rat β1-adrenergic receptor

Linda A. Rezmann-Vitti et al.

JOURNAL OF MEDICINAL CHEMISTRY (2006)

Article Biochemical Research Methods

Analysis of apoptosis by propidium iodide staining and flow cytometry

Carlo Riccardi et al.

NATURE PROTOCOLS (2006)

Article Cell Biology

A rapid method for assessing the distribution of gold labeling on thin sections

JM Lucocq et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Methamphetamine produces neuronal inclusions in the nigrostriatal system and in PC12 cells

F Fornai et al.

JOURNAL OF NEUROCHEMISTRY (2004)

Article Neurosciences

Noradrenergic inhibition of midbrain dopamine neurons

CA Paladini et al.

JOURNAL OF NEUROSCIENCE (2004)

Article Biochemistry & Molecular Biology

Alpha-1B adrenergic receptor knockout mice are protected against methamphetamine toxicity

G Battaglia et al.

JOURNAL OF NEUROCHEMISTRY (2003)

Review Geriatrics & Gerontology

Staging of brain pathology related to sporadic Parkinson's disease

H Braak et al.

NEUROBIOLOGY OF AGING (2003)

Article Clinical Neurology

Noradrenergic loss enhances MDMA toxicity and induces ubiquitin-positive striatal whorls

M Ferrucci et al.

NEUROLOGICAL SCIENCES (2002)

Review Pharmacology & Pharmacy

The role of catecholamines in seizure susceptibility: new results using genetically engineered mice

D Weinshenker et al.

PHARMACOLOGY & THERAPEUTICS (2002)

Review Behavioral Sciences

The role of the locus coeruleus in the development of Parkinson's disease

M Gesi et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2000)