Related references
Note: Only part of the references are listed.CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential
Isabel R. Schlaepfer et al.
ENDOCRINOLOGY (2020)
REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet
Karine Dumas et al.
FASEB JOURNAL (2020)
Increased Purinergic Responses Dependent on P2Y2 Receptors in Hepatocytes from CCl4-Treated Fibrotic Mice
Erandi Velazquez-Miranda et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
P2Y(2)Receptor Promotes High-Fat Diet-Induced Obesity
Yue Zhang et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice
Si-wei Wang et al.
NUTRITION & DIABETES (2020)
Purinergic signalling in liver diseases: Pathological functions and therapeutic opportunities
Ping Wang et al.
JHEP REPORTS (2020)
Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance
Lia R. Edmunds et al.
MOLECULAR METABOLISM (2020)
Pathogenesis of Nonalcoholic Steatohepatitis: An Overview
Gopanandan Parthasarathy et al.
HEPATOLOGY COMMUNICATIONS (2020)
Hepatic Interferon Regulatory Factor 6 Alleviates Liver Steatosis and Metabolic Disorder by Transcriptionally Suppressing Peroxisome Proliferator-Activated Receptor γ in Mice
Jingjing Tong et al.
HEPATOLOGY (2019)
Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications
Michele Longo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
NAFLD and Diabetes: Two Sides of the Same Coin? Rationale for Gene-Based Personalized NAFLD Treatment
Ming-Feng Xia et al.
FRONTIERS IN PHARMACOLOGY (2019)
Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators
Elena Piccinin et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)
Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD
Daniel Garcia et al.
CELL REPORTS (2019)
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
David Hojland Ipsen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue
Lingyan Wu et al.
FRONTIERS IN PHYSIOLOGY (2018)
Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models
Ryan M. Esquejo et al.
EBIOMEDICINE (2018)
AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo
Marc Foretz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome
Julian Merz et al.
BASIC RESEARCH IN CARDIOLOGY (2018)
Constitutive P2Y(2) receptor activity regulates basal lipolysis in human adipocytes
Seema B. Ali et al.
JOURNAL OF CELL SCIENCE (2018)
NAFLD and diabetes mellitus
Herbert Tilg et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet
Angela Woods et al.
CELL REPORTS (2017)
Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function
Emilio P. Mottillo et al.
CELL METABOLISM (2016)
Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice
Camella G. Wilson et al.
ENDOCRINOLOGY (2016)
Upregulation of P2Y2 nucleotide receptor in human hepatocellular carcinoma cells
Eunyoung Tak et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2016)
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
Elena Buzzetti et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background
Jinsheng Yu et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2016)
Targeting renal purinergic signalling for the treatment of lithium-induced nephrogenic diabetes insipidus
B. K. Kishore et al.
ACTA PHYSIOLOGICA (2015)
Honokiol activates the LKB1-AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes
Min Suk Seo et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2015)
Luteolin Attenuates Hepatic Steatosis and Insulin Resistance Through the Interplay Between the Liver and Adipose Tissue in Mice with Diet-Induced Obesity
Eun-Young Kwon et al.
DIABETES (2015)
P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy
Bryan C. Tackett et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2014)
Hepatic PPARγ and LXRα independently regulate lipid accumulation in the livers of genetically obese mice
Kimihiko Matsusue et al.
FEBS LETTERS (2014)
Purinergic signalling in the liver in health and disease
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2014)
Mitochondrial Adaptations and Dysfunctions in Nonalcoholic Fatty Liver Disease
Karima Begriche et al.
HEPATOLOGY (2013)
Immune and inflammatory pathways in NASH
Michal Ganz et al.
HEPATOLOGY INTERNATIONAL (2013)
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
Morgan D. Fullerton et al.
NATURE MEDICINE (2013)
PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion
E. Matthew Morris et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications
Kenneth Cusi
GASTROENTEROLOGY (2012)
Purinergic P2Y2 Receptors Promote Neutrophil Infiltration and Hepatocyte Death in Mice With Acute Liver Injury
Cemil Korcan Ayata et al.
GASTROENTEROLOGY (2012)
Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis
Julia Monsenego et al.
JOURNAL OF HEPATOLOGY (2012)
Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice
Michal Aharoni-Simon et al.
LABORATORY INVESTIGATION (2011)
Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment
Briohny W. Smith et al.
NATURE REVIEWS ENDOCRINOLOGY (2011)
Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor α expression
Alexander R. Moschen et al.
GUT (2010)
The Role of Lipid Metabolism in the Pathogenesis of Alcoholic and Nonalcoholic Hepatic Steatosis
Margaret S. Sozio et al.
SEMINARS IN LIVER DISEASE (2010)
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARγ in promoting steatosis
Jie Zhou et al.
GASTROENTEROLOGY (2008)
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
Adilson Guilherme et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
Sibylle Jaeger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Metabolic control through the PGC-1 family of transcription coactivators
JD Lin et al.
CELL METABOLISM (2005)
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
DE Kleiner et al.
HEPATOLOGY (2005)