4.7 Article

Nrf2 Activation Attenuates Acrylamide-Induced Neuropathy in Mice

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice

Frederick Adams Ekuban et al.

Summary: This study revealed the significant role of Nrf2 in acrylamide-induced neurotoxicity, with Nrf2-knockout mice showing more severe neurodegeneration and inflammation when exposed to acrylamide.

TOXICOLOGY (2021)

Review Biochemistry & Molecular Biology

KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease

Sharadha Dayalan Naidu et al.

OPEN BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Efficacy of Sulforaphane in Neurodegenerative Diseases

Giovanni Schepici et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Cell Biology

Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1

Takafumi Suzuki et al.

CELL REPORTS (2019)

Review Biochemistry & Molecular Biology

A Dual Role of Heme Oxygenase-1 in Cancer Cells

Shih-Kai Chiang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Psychiatry

From anatomy to function: the role of the somatosensory cortex in emotional regulation

Erika Kropf et al.

BRAZILIAN JOURNAL OF PSYCHIATRY (2019)

Article Toxicology

Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles

Radwa Sehsah et al.

PARTICLE AND FIBRE TOXICOLOGY (2019)

Article Pharmacology & Pharmacy

Neuroprotective effect of an Nrf2-ARE activator identified from a chemical library on dopaminergic neurons

Yasuhiko Izumi et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2018)

Review Cell Biology

A review on heme oxygenase-1 induction: is it a necessary evil

Ajaz Ahmad Waza et al.

INFLAMMATION RESEARCH (2018)

Review Biochemistry & Molecular Biology

Transcriptional Regulation by Nrf2

Claudia Tonelli et al.

ANTIOXIDANTS & REDOX SIGNALING (2018)

Review Biochemistry & Molecular Biology

Nrf2, the Master Regulator of Anti-Oxidative Responses

Sandra Vomund et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemistry & Molecular Biology

Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium

Gobinath Shanmugam et al.

REDOX BIOLOGY (2017)

Review Biochemistry & Molecular Biology

HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation

Mariapaola Nitti et al.

ANTIOXIDANTS (2017)

Article Environmental Sciences

Acrylamide content in cigarette mainstream smoke and estimation of exposure to acrylamide from tobacco smoke in Poland

Hanna Mojska et al.

ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE (2016)

Article Pharmacology & Pharmacy

Partial contribution of the Keap1-Nrf2 system to cadmium-mediated metallothionein expression in vascular endothelial cells

Yasuhiro Shinkai et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2016)

Article Geriatrics & Gerontology

Dna Demethylation Upregulated nrf2 expression in alzheimer's Disease cellular Model

Huimin Cao et al.

FRONTIERS IN AGING NEUROSCIENCE (2016)

Article Neurosciences

Toll-Like Receptor 4 Deficiency Impairs Motor Coordination

Jian-Wei Zhu et al.

FRONTIERS IN NEUROSCIENCE (2016)

Article Multidisciplinary Sciences

Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner

Shasha Tao et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

Metallothionein plays a prominent role in the prevention nephropathy by sulforaphane via up-regulation of Nrf2

Hao Wu et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Article Food Science & Technology

Suppression of LPS-induced transcription and cytokine secretion by the dietary isothiocyanate sulforaphane

Danielle L. Folkard et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2014)

Review Biochemistry & Molecular Biology

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

John D. Hayes et al.

TRENDS IN BIOCHEMICAL SCIENCES (2014)

Review Neurosciences

Focal dystonia in musicians: linking motor symptoms to somatosensory dysfunction

Juergen Konczak et al.

FRONTIERS IN HUMAN NEUROSCIENCE (2013)

Review Cell Biology

Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases

Andrea Tarozzi et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Article Multidisciplinary Sciences

Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis

Chaeuk Chung et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Environmental Sciences

Molecular Mechanism of Acrylamide Neurotoxicity: Lessons Learned from Organic Chemistry

Richard M. LoPachin et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2012)

Review Biochemistry & Molecular Biology

Molecular mechanisms underlying chemical liver injury

Xinsheng Gu et al.

EXPERT REVIEWS IN MOLECULAR MEDICINE (2012)

Article Biochemistry & Molecular Biology

Schisandrin B exhibits anti-inflammatory activity through modulation of the redox-sensitive transcription factors Nrf2 and NF-κB

Rahul Checker et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Article Pharmacology & Pharmacy

Sulforaphane protects SK-N-SH cells against antipsychotic-induced oxidative stress

Sergi Mas et al.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2012)

Article Cell Biology

Isothiocyanates inhibit psoriasis-related proinflammatory factors in human skin

Hila Yehuda et al.

INFLAMMATION RESEARCH (2012)

Article Biochemistry & Molecular Biology

Amyloid neurotoxicity is attenuated by metallothionein: dual mechanisms at work

Jong-Heon Kim et al.

JOURNAL OF NEUROCHEMISTRY (2012)

Article Biochemical Research Methods

NIH Image to ImageJ: 25 years of image analysis

Caroline A. Schneider et al.

NATURE METHODS (2012)

Review Toxicology

The cytoprotective role of the Keap1-Nrf2 pathway

Liam Baird et al.

ARCHIVES OF TOXICOLOGY (2011)

Review Neurosciences

Brain regions and genes affecting limb-clasping responses

R. Lalonde et al.

BRAIN RESEARCH REVIEWS (2011)

Article Environmental Sciences

Isothiocyanates Reduce Mercury Accumulation via an Nrf2-Dependent Mechanism during Exposure of Mice to Methylmercury

Takashi Toyama et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2011)

Review Biochemistry & Molecular Biology

Redox biochemistry of mammalian metallothioneins

Wolfgang Maret

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2011)

Review Oncology

A Review of Metallothionein Isoforms and their Role in Pathophysiology

N. Thirumoorthy et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2011)

Article Cell Biology

Sulforaphane suppresses LPS-induced inflammation in primary rat microglia

Lars-Ove Brandenburg et al.

INFLAMMATION RESEARCH (2010)

Review Nutrition & Dietetics

Toxicity of acrylamide and evaluation of its exposure in baby foods

Pinar Erkekoglu et al.

NUTRITION RESEARCH REVIEWS (2010)

Article Multidisciplinary Sciences

Electrophilic tuning of the chemoprotective natural product sulforaphane

Young-Hoon Ahn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

Michael McMahon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Agriculture, Multidisciplinary

Modulation of Phase II Enzymes by Sulforaphane: Implications for Its Cardioprotective Potential

Cristina Angeloni et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)

Article Cell Biology

The Nrf2-ARE Pathway An Indicator and Modulator of Oxidative Stress in Neurodegeneration

Jeffrey A. Johnson et al.

MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS (2008)

Article Immunology

The transcription factor Nrf2 is a therapeutic target against brain inflammation

Nadia G. Innamorato et al.

JOURNAL OF IMMUNOLOGY (2008)

Review Food Science & Technology

Direct and indirect antioxidant properties of inducers of cytoprotective proteins

Albena T. Dinkova-Kostova et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2008)

Article Biochemistry & Molecular Biology

Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity

Takashi Toyama et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Neurosciences

Empathy for pain and touch in the human somatosensory cortex

Ilaria Bufalari et al.

CEREBRAL CORTEX (2007)

Review Biochemistry & Molecular Biology

Molecular basis for chemoprevention by sulforaphane: a comprehensive review

N. Juge et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2007)

Article Food Science & Technology

Influence of roasting conditions on the acrylamide content and the color of roasted almonds

Helen Lukac et al.

JOURNAL OF FOOD SCIENCE (2007)

Review Biochemistry & Molecular Biology

Molecular basis of heme oxygenase-1 induction: Implications for chemoprevention and chemoprotection

A Prawan et al.

ANTIOXIDANTS & REDOX SIGNALING (2005)

Article Food Science & Technology

Formation of acrylamide in a processed food model system, and examination of inhibitory conditions

K Ishihara et al.

JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN (2005)

Review Biotechnology & Applied Microbiology

The carcinogenicity of acrylamide

JM Rice

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2005)

Article Pharmacology & Pharmacy

Clinical perspectives on xenobiotic-induced hepatotoxicity

B Gunawan et al.

DRUG METABOLISM REVIEWS (2004)

Review Biochemistry & Molecular Biology

Nrf2-Keap1 defines a physiologically important stress response mechanism

H Motohashi et al.

TRENDS IN MOLECULAR MEDICINE (2004)

Article Neurosciences

The changing view of acrylamide neurotoxicity

RM LoPachin

NEUROTOXICOLOGY (2004)

Article Biochemistry & Molecular Biology

Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts

A Hayashi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Review Reproductive Biology

Effects of acrylamide on rodent reproductive performance

RW Tyl et al.

REPRODUCTIVE TOXICOLOGY (2003)

Article Multidisciplinary Sciences

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

AT Dinkova-Kostova et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Agriculture, Multidisciplinary

Analysis of acrylamide, a carcinogen formed in heated foodstuffs

E Tareke et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2002)

Review Neurosciences

Nerve terminals as the primary site of acrylamide action: A hypothesis

RM LoPachin et al.

NEUROTOXICOLOGY (2002)

Article Neurosciences

Differential coding of pain intensity in the human primary and secondary somatosensory cortex

L Timmermann et al.

JOURNAL OF NEUROPHYSIOLOGY (2001)

Article Biochemistry & Molecular Biology

Nuclear factor κB is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms

E Heiss et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Chemistry, Medicinal

Acrylamide:: A cooking carcinogen?

E Tareke et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2000)