Journal
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
Volume 73, Issue 2, Pages 210-220Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09637486.2021.1941803
Keywords
Orthodox fasting; time-restricted eating; adiponectin; lipids; insulin resistance; body weight
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Funding
- Hellenic Diabetes Association [1395/2020]
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The study found that Orthodox fasting led to increased adiponectin levels and decreased body fat percentage, with an inverse correlation between adiponectin and waist circumference. These results suggest favorable metabolic effects of Orthodox fasting.
The exact mechanisms mediating the metabolic effects of Orthodox fasting remain unclear. Plasma adiponectin, biochemical and anthropometrical data were evaluated in 55 Orthodox fasters (OF) and 42 time-restricted eating controls (all women, mean age 47.8 years) at three time points: baseline, end of the dietary intervention (7 weeks) and 5 weeks after participants returned to their typical dietary habits (12 weeks from baseline). In the OF group, there was an increase in adiponectin values at 12 weeks compared with baseline (9815.99 vs 8983.52 mg/ml, p = 0.02) and a reduction in body fat mass between baseline and 12 weeks (35.44 vs 32.17%, p = 0.004) and between 7 and 12 weeks (35.33 vs 32.17%, p = 0.003). In the same group, an inverse correlation between adiponectin and waist circumference values was observed over the entire study period. Our results provide novel evidence that Orthodox fasting has favourable metabolic effects related to improved adiponectin concentrations.
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