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Acquired epidermodysplasia verruciformis: clinical presentation and treatment update

Journal

INTERNATIONAL JOURNAL OF DERMATOLOGY
Volume 61, Issue 11, Pages 1325-1335

Publisher

WILEY
DOI: 10.1111/ijd.15857

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Acquired epidermodysplasia verruciformis (AEV) is a form of epidermodysplasia verruciformis (EV) commonly found in immunocompromised patients, often associated with HPV. Treatment options include various topical medications, vaccines, and improving cellular immunity.
Acquired epidermodysplasia verruciformis (AEV) is a form of epidermodysplasia verruciformis (EV) that is most commonly found in immunocompromised or immunosuppressed patients. EV is commonly associated with human papillomavirus (HPV), which is often found in EV and AEV lesions. Clinical presentation of AEV in patients with organ transplantation, HIV+, congenital HIV+, hematological diseases, and other iatrogenic immunosuppression are reviewed. Treatment options include topical cidofovir, topical retinoids, topical imiquimod, topical glycolic acid, HPV 9-valent vaccine, acitretin, improving cellular immunity, and changing transplant medication to mycophenolate mofetil.

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