Temperature-resistant and solvent-tolerant lipases as industrial biocatalysts: Biotechnological approaches and applications

The development of new biocatalytic systems to replace the chemical catalysts, with suitable characteristics in terms of efficiency, stability under high temperature reactions and in the presence of organic solvents, reusability, and eco-friendliness is considered a very important step to move towards the green processes. From this basis, the use of lipase as a catalyst is highly desired for many industrial applications because it offers the reactions in which could be used, stability in harsh conditions, reusability and a greener process. Therefore, the introduction of temperature-resistant and solvent-tolerant lipases have become essential and ideal for industrial applications. Temperature-resistant and solvent-tolerant lipases have been involved in many large-scale applications including biodiesel, detergent, food, pharmaceutical, organic synthesis, biosensing, pulp and paper, textile, animal feed, cosmetics, and leather industry. So, the present review provides a comprehensive overview of the industrial use of lipase. Moreover, special interest in biotechnological and biochemical techniques for enhancing temperature-resistance and solvent-tolerance of lipases to be suitable for the industrial uses.

Automated summary

The development of new biocatalytic systems, particularly temperature-resistant and solvent-tolerant lipases, is crucial for industrial applications in biodiesel, detergent, food, pharmaceutical, and other industries. The enhancement of lipase temperature-resistance and solvent-tolerance through biotechnological and biochemical techniques is essential for industrial use.