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Comparative analysis of various extraction processes based on economy, eco-friendly, purity and recovery of polyhydroxyalkanoate: A review

Journal

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 183, Issue -, Pages 1881-1890

Publisher

ELSEVIER
DOI: 10.1016/j.ijbiomac.2021.06.007

Keywords

PHA; Halogenated solvents; Non-PHA cell mass; Green solvents; Biopolymers

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Bioplastics are a promising alternative to traditional plastics as they are synthesized by microorganisms and are biodegradable. However, their production cost is high and various extraction methods for polyhydroxyalkanoate (PHA) have been reported with each method having its own advantages and disadvantages.
Bioplastics have been an interesting area of research and development in the last few decades. Normal plastics are made out of petroleum products, which is a non-renewable resource. Apart from that, its non-biodegradable nature makes it a serious threat to the environment, and hence a better alternative is needed. Bioplastics are synthesized by microorganisms and are biodegradable; this property makes them a promising alternative to normal plastic. However, the major drawback related to bioplastic is the high cost of its production. Polyhydroxyalkanoate (PHA) is a very popular biopolymer produced by different types of microbes. The review focuses on the different methods of extraction of PHA based on the percentage of purity, recovery, eco-friendly, and cost-effectiveness. There is a wide array of extraction methods reported to date, wherein there is the involvement of different types of solvents (like halogenated, non-halogenated, and green solvents) or mechanical or enzymatic methods. Each extraction process has its advantages and disadvantages. In this study, we have attempted to present a structured comparison of these different methods and highlight the factors that can be addressed for better extraction of PHA thereby making it a feasible alternative to commercial synthetic plastic.

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