4.6 Article

The discovery of indolone GW5074 during a comprehensive search for non-polyamine-based polyamine transport inhibitors

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas

Aaminah Khan et al.

Summary: DIPG is a deadly childhood brain tumor with limited treatment options. Targeting both polyamine synthesis and uptake can lead to prolonged survival in animal models of this incurable disease.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

ATP13A2 deficiency disrupts lysosomal polyamine export

Sarah van Veen et al.

NATURE (2020)

Article Chemistry, Medicinal

Spermine-NBD as fluorescent probe for studies of the polyamine transport system in Leishmania donovani

Elodie Jagu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)

Article Biochemistry & Molecular Biology

Targeting of early endosomes by autophagy facilitates EGFR recycling and signalling

Jane Fraser et al.

EMBO REPORTS (2019)

Review Chemistry, Multidisciplinary

Polyamines: Bio-Molecules with Diverse Functions in Plant and Human Health and Disease

Avtar K. Handa et al.

FRONTIERS IN CHEMISTRY (2018)

Review Oncology

Polyamine metabolism and cancer: treatments, challenges and opportunities

Robert A. Casero et al.

NATURE REVIEWS CANCER (2018)

Article Multidisciplinary Sciences

Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis

Chunhua Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Pharmacology & Pharmacy

Budesonide plus formoterol fumarate dihydrate for the treatment of asthma

Ole D. Wolthers

EXPERT OPINION ON PHARMACOTHERAPY (2016)

Article Biochemistry & Molecular Biology

Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by Subtype-selective Antagonist Drugs

John D. Pediani et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Review Biochemistry & Molecular Biology

Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell

Leonor Miller-Fleming et al.

JOURNAL OF MOLECULAR BIOLOGY (2015)

Article Chemistry, Medicinal

Polyamine Transport Inhibitors: Design, Synthesis, and Combination Therapies with Difluoromethylornithine

Aaron Muth et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

ZebraBeat: a flexible platform for the analysis of the cardiac rate in zebrafish embryos

Elisa De Luca et al.

SCIENTIFIC REPORTS (2014)

Review Biochemistry & Molecular Biology

Small Molecules for Dissecting Endomembrane Trafficking: A Cross-Systems View

Kiril Mishev et al.

CHEMISTRY & BIOLOGY (2013)

Review Endocrinology & Metabolism

KATP channels and islet hormone secretion: new insights and controversies

Frances M. Ashcroft et al.

NATURE REVIEWS ENDOCRINOLOGY (2013)

Article Multidisciplinary Sciences

Serum Metabolomics of Slow vs. Rapid Motor Progression Parkinson's Disease: a Pilot Study

James R. Roede et al.

PLOS ONE (2013)

Review Biochemistry & Molecular Biology

Recent advances in the molecular biology of metazoan polyamine transport

R. Poulin et al.

AMINO ACIDS (2012)

Article Biochemistry & Molecular Biology

Loop Diuretic and Ion-binding Residues Revealed by Scanning Mutagenesis of Transmembrane Helix 3 (TM3) of Na-K-Cl Cotransporter (NKCC1)

Suma Somasekharan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge

Bahne Stechmann et al.

Editorial Material Biochemistry & Molecular Biology

Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders

Steven M. Smith et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2009)

Article Cell Biology

Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg et al.

NATURE CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network

Robert A. Spooner et al.

BIOCHEMICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

Identification and characterization of a diamine exporter in colon epithelial cells

Takeshi Uemura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Activated K-RAS increases polyamine uptake in human colon cancer cells through modulation of caveolar endocytosis

Upal K. Basu Roy et al.

MOLECULAR CARCINOGENESIS (2008)

Article Microbiology

Glibenclamide, a blocker of K+ATP channels, shows antileishmanial activity in experimental murine cutaneous leishmaniasis

Xenon Serrano-Martin et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)

Article Biochemistry & Molecular Biology

A fluorescent probe of polyamine transport accumulates into intracellular acidic vesicles via a two-step mechanism

D Soulet et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer

N Babbar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

Exo1: A new chemical inhibitor of the exocytic pathway

Y Feng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Chemistry, Medicinal

Amino acid/spermine conjugates: Polyamine amides as potent spermidine uptake inhibitors

MR Burns et al.

JOURNAL OF MEDICINAL CHEMISTRY (2001)

Article Chemistry, Medicinal

The discovery of potent cRaf1 kinase inhibitors

K Lackey et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)