Journal
INORGANICA CHIMICA ACTA
Volume 522, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ica.2021.120379
Keywords
Coordination polymer; CO2 conversion; Intestinal epithelial cell; Western blotting
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By applying a dual-ligand strategy, two transition metal coordination polymers were synthesized and showed high catalytic activity in the presence of a cocatalyst under mild and solvent-free conditions, with the ability to chemically fix cyclic carbonates and carbon dioxide.
By virtue of a dual-ligand strategy, two transition metal coordination polymers of {[Ni-2(NDC)(2)(L-1)(H2O)(2)(H2O)]. (DMF)(2)(H2O)}(n) (1, L-1 = 3,3'-azobis pyridine) and [Mn(NDC)(L-2)(H2O)](n) (2, L-2 = 1,4-bis(1H-benzo[d]imidazol-1-yl)butane) have been synthesized via the corresponding metal salts reacting with the 1,4-naphthalene dicarboxylic acid (H2NDC) in the existence of distinct nitrogen-donor co-ligands. Given the permanently microporous nature, moderate CO2 sorption capacity as well as high density of the open metals positions, the activated 1 revealed the chemical fixation of the cyclic carbonates and carbon dioxide or an efficient activity of catalysis in the existence of the cocatalyst under the mild and solvent-free conditions. To evaluate the activity of the compound against intestinal polyps, following experiments were conducted. The Cell Counting Kit-8 (CCK-8) method was implemented to evaluate the inhibitory effects of these two compounds against the intestinal epithelial cells. Next, the western blotting was conducted and the apoptotic protein Bcl-2 expression levels was determined as well.
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