Journal
IMMUNITY
Volume 54, Issue 8, Pages 1633-1635Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2021.07.013
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Funding
- European Research Council (ERC) [715772]
- Dutch Research Council (NWO-VIDI) [016.178.056]
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The study found that Bifidobacteria can produce immunoregulatory compounds using milk sugars, aiding in immune tolerance and reducing intestinal inflammation in infants.
Immune-system maturation starts early in life, but studies investigating immune-system education in human infants remain scarce. In a recent issue of Cell, Henrick et al. study early gut microbiota and immune-system development in two infant cohorts. The authors describe that Bifidobacteria can use milk sugars to produce immunoregulatory compounds that induce immune tolerance and reduce intestinal inflammation.
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