4.7 Article

CoronaPep: An Anti-Coronavirus Peptide Generation Tool

Publisher

IEEE COMPUTER SOC
DOI: 10.1109/TCBB.2021.3064630

Keywords

COVID-19; Peptides; Tools; Proteins; Tides; Software; Bioinformatics; Anti-coronavirus peptides; coronavirus; COVID-19; fingerprinting

Funding

  1. Ministry of Science and Technology of China [2016YFA0501703]
  2. National Natural Science Foundation of China [61832019, 61503244]
  3. Science and Technology Commission of Shanghai Municipality [19430750600]
  4. Natural Science Foundation of Henan Province [162300410060]
  5. SJTU JiRLMDS Joint Research Fund
  6. Joint Research Funds for Medical and Engineering and Scientific Research at Shanghai Jiao Tong University [YG2017ZD14]

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The novel coronavirus (COVID-19) has become a global pandemic, requiring urgent vaccine development. The CoronaPep tool is designed to quickly identify anti-coronavirus targets and provide precise anti-viral peptides, which can aid researchers in oncology and drug design.
The novel coronavirus (COVID-19) infections have adopted the shape of a global pandemic now, demanding an urgent vaccine design. The current work reports contriving an anti-coronavirus peptide scanner tool to discern anti-coronavirus targets in the embodiment of peptides. The proffered CoronaPep tool features the fast fingerprinting of the anti-coronavirus target serving supreme prominence in the current bioinformatics research. The anti-coronavirus target protein sequences reported from the current outbreak are scanned against the anti-coronavirus target data-sets via CORONAPEP which provides precision-based anti-coronavirus peptides. This tool is specifically for the coronavirus data, which can predict peptides from the whole genome, or a gene or protein's list. Besides it is relatively fast, accurate, userfriendly and can generate maximum output from the limited information. The availability of tools like CORONAPEP will immeasurably perquisite researchers in the discipline of oncology and structure-based drug design.

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