4.2 Review

A practical guide to chimerism analysis: Review of the literature and testing practices worldwide

Related references

Note: Only part of the references are listed.
Article Medical Laboratory Technology

Development and performance of a next generation sequencing (NGS) assay for monitoring of mixed chimerism

Linnea Pettersson et al.

Summary: This study aimed to evaluate a novel NGS-based assay for monitoring mixed chimerism, and found that NGS demonstrated high sensitivity and good accuracy, outperforming real-time PCR and fragment analysis techniques.

CLINICA CHIMICA ACTA (2021)

Review Genetics & Heredity

The Nexus of cfDNA and Nuclease Biology

Diana S. C. Han et al.

Summary: Cell-free DNA (cfDNA) serves as a widely used noninvasive biomarker in the diagnosis and prognosis of diseases. The balance between cfDNA generation and clearance is crucial in maintaining health and managing diseases, with plasma nuclease activity linked to various pathologies and changes in cfDNA fragmentation. Further research on factors influencing cfDNA levels and fragmentomic profiles provides insights into the biology of cfDNA.

TRENDS IN GENETICS (2021)

Review Oncology

The molecular profiling of solid tumors by liquid biopsy: a position paper of the AIOM-SIAPEC-IAP-SIBioC-SIC-SIF itallan Scientific Societies

A. Russo et al.

Summary: Liquid biopsy, utilizing various biological fluids as substitutes for neoplastic tissue to gather crucial information about tumors, is widely employed in clinical practice. Besides tumor tissue, other biological samples can also be used to identify predictive biomarkers for response or resistance to targeted treatments, with new applications emerging as useful clinical tools in the near future.

ESMO OPEN (2021)

Article Biotechnology & Applied Microbiology

Evaluation of host-based molecular markers for the early detection of human sepsis

Elisabeth Ullrich et al.

JOURNAL OF BIOTECHNOLOGY (2020)

Review Medical Laboratory Technology

Cell free DNA as a diagnostic and prognostic marker for cardiovascular diseases

Iuliia A. Polina et al.

CLINICA CHIMICA ACTA (2020)

Review Biochemistry & Molecular Biology

Liquid Biopsy for the Diagnosis of Viral Hepatitis, Fatty Liver Steatosis, and Alcoholic Liver Diseases

Ciniso Sylvester Shabangu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

Evaluating the quantity, quality and size distribution of cell-free DNA by multiplex droplet digital PCR

Miguel Alcaide et al.

SCIENTIFIC REPORTS (2020)

Review Medicine, General & Internal

Cell-free nucleic acid patterns in disease prediction and monitoring-hype or hope?

Adriana Torres Crigna et al.

EPMA JOURNAL (2020)

Article Hematology

Ultra-Sensitive Droplet Digital PCR for the Assessment of Microchimerism in Cellular Therapies

David Kliman et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2018)

Article Medical Laboratory Technology

Cell-free DNA characteristics and chimerism analysis in patients after allogeneic cell transplantation

Jesus Duque-Afonso et al.

CLINICAL BIOCHEMISTRY (2018)

Review Medical Laboratory Technology

Cell-free DNA as a biomarker in stroke: Current status, problems and perspectives

Kristina V. Glebova et al.

CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES (2018)

Review Medicine, General & Internal

Technical Advances in the Measurement of Residual Disease in Acute Myeloid Leukemia

Gregory W. Roloff et al.

JOURNAL OF CLINICAL MEDICINE (2017)

Article Respiratory System

Myriad Applications of Circulating Cell-Free DNA in Precision Organ Transplant Monitoring

Philip Burnham et al.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2017)

Review Hematology

Current Use and Trends in Hematopoietic Cell Transplantation in the United States

Anita D'Souza et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2017)

Article Medical Laboratory Technology

Early mixed hematopoietic chimerism detection by digital droplet PCR in patients undergoing gender-mismatched hematopoietic stem cell transplantation

Miguel Waterhouse et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2017)

Article Oncology

A technical application of quantitative next generation sequencing for chimerism evaluation

Michelangelo Aloisio et al.

MOLECULAR MEDICINE REPORTS (2016)

Article Multidisciplinary Sciences

Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends

K. C. Allen Chan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Immunology

Donor-Specific Anti-HLA Antibodies in Allogeneic Hematopoietic Stem Cell Transplantation

Sarah Morin-Zorman et al.

FRONTIERS IN IMMUNOLOGY (2016)

Review Immunology

Immune Reconstitutional after Allogeneic Hematopoietic Stem Cell Transplantation

Justyna Ogonek et al.

FRONTIERS IN IMMUNOLOGY (2016)

Article Multidisciplinary Sciences

Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing

Rebecca W. Y. Chan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Genetics & Heredity

Application of Next-generation Sequencing Technology in Forensic Science

Yaran Yang et al.

GENOMICS PROTEOMICS & BIOINFORMATICS (2014)

Article Hematology

Genome-wide Profiling in AML Patients Relapsing after Allogeneic Hematopoietic Cell Transplantation

Miguel Waterhouse et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2011)

Article Medicine, General & Internal

Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation.

Luca Vago et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Review Biophysics

Mixed chimerism in SCT: conflict or peaceful coexistence?

J. L. Liesveld et al.

BONE MARROW TRANSPLANTATION (2008)

Article Biochemical Research Methods

Statistical significance of quantitative PCR

Yann Karlen et al.

BMC BIOINFORMATICS (2007)

Review Biophysics

How and when should we monitor chimerism after allogeneic stem cell transplantation?

P Bader et al.

BONE MARROW TRANSPLANTATION (2005)