Journal
HEART RHYTHM
Volume 18, Issue 10, Pages 1772-1779Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.hrthm.2021.06.1189
Keywords
Bipolar radiofrequency ablation; Circuit impedance; Transmural lesion; Transmyocardial electrogram amplitude; Ventricular tachycardia ablation
Categories
Funding
- Heart and stroke mid-career investigator award of Ontario
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Bipolar radiofrequency (RF) ablation at power of 20-30 W was found to provide an ideal balance of safety and efficacy, while caution should be exercised with power >40 W due to a high incidence of steam pops. Monitoring lesion transmurality and avoiding steam pops were best achieved using transmyocardial bipolar electrogram (EGM) amplitude and circuit impedance, respectively.
BACKGROUND The safety and efficacy parameters for bipolar radiofrequency (RF) ablation are not well defined. OBJECTIVE The purpose of this study was to investigate the safe range of power, utility of transmyocardial bipolar electrogram (EGM) amplitude, and circuit impedance in ablation monitoring. METHODS Sixteen beating ex vivo human and swine hearts were studied in a Langendorff setup. Ninety-two bipolar ablations using two 4-mm irrigated catheters were performed at settings of 20-50 W, 60 seconds, and 30 mL/min irrigation in the left ventricle. RESULTS For low-power ablations (20 and 30 W), transmurality was observed in 29 of 38 (76%) and 10 of 28 (36%) ablations for tissue thickness <17 mm and >17 mm, respectively. For high-power ablations (40 and 50 W), transmurality was observed in 5 of 7 (71%) and 7 of 19 (37%) ablations for tissue thickness <17 mm and >17 mm, respectively. Steam pop occurrence for low-and high-power ablations was 11 of 66 (16%) and 16 of 26 (62%), respectively (P = .0001), respectively. Lesion depth (limited by transmurality) was 12.0 +/- 5.7 mm and 12.3 +/- 5.8 mm, respectively (P = 1). Transmyocardial EGM amplitude decrement >60% strongly predicted transmurality (area under the curve [AUC] 0.8), and circuit impedance decrement >26% predicted steam pops (AUC 0.75). Half-normal saline did not affect transmurality or incidence of steam pops compared to normal saline irrigation. CONCLUSION Bipolar RF ablation at power of 20-30 W provided an ideal balance of safety and efficacy, whereas power >40 W should be used with caution due to the high incidence of steam pops. Lesion transmurality monitoring and steam pop avoidance were best achieved using transmyocardial bipolar EGM voltage and circuit impedance, respectively.
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