Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 43, Issue 12, Pages 3775-3787Publisher
WILEY
DOI: 10.1002/hed.26872
Keywords
diagnosis; melanocytes; melanoma; mouth mucosa; nevus; pigmentation
Categories
Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior [001]
- Fundacao de Amparo a Pesquisa do Estado de Minas Gerais
- Pro-Reitoria de Pesquisa, Universidade Federal de Minas Gerais
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This study analyzed the clinical and demographic features of oral pigmented lesions, finding that solitary lesions are more common and summarizing the clinical differential diagnosis features, including age, site, and appearance characteristics.
Background The aim was to analyze the frequency, clinical and demographic features of solitary and multiple/diffuse oral pigmented lesions submitted to histopathological examination, and to summarize the features that guide the clinical differential diagnosis. Methods Clinical and demographic data were retrieved from biopsy records and descriptive statistics were performed. Results Nine hundred and five (0.51%) oral pigmented lesions were retrieved among 177 356 specimens, being 95.9% solitary and 4.1% multiple/diffuse lesions. Regardless the overlapping clinical presentation, age, site, association with amalgam restoration, and a nodular appearance may help in the clinical differential diagnosis of solitary oral pigmentations. Patient's habits, site, and systemic signs and symptoms are helpful in the clinical differential diagnosis of multiple/diffuse lesions. Conclusions Oral pigmented lesions are a rare diagnosis in oral pathology and solitary lesions are more commonly submitted to biopsy. Some key features help in the differential diagnosis, though biopsy can be warranted in doubtful cases.
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