4.7 Article

Assembly and annotation of whole-genome sequence of Fusarium equiseti

Journal

GENOMICS
Volume 113, Issue 4, Pages 2870-2876

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ygeno.2021.06.019

Keywords

Fusarium; Phylogeny; Zearalenone; Trichothecene; Whole-genome sequencing

Funding

  1. Youth Fund for Gansu Academy of Agricultural Sciences [2019GAAS34]
  2. Special Fund for Agro-Scientific Research in the Public Interest [201503112]

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Fusarium equiseti, a plant pathogen with potential probiotic effects, has unclear molecular mechanisms. Our genomic sequence analysis provides a valuable resource for future studies on gene expression, regulation, function, evolution, disease prevention, and control related to this pathogen.
Fusarium equiseti is a plant pathogen with a wide range of hosts and diverse effects, including probiotic effects. However, the molecular mechanisms underlying these effects remain unclear, hindering its effective utilization. The final assembly included 16 scaffolds of contiguous sequence without gaps. The total sequence length was 40,776,005 bp, and the GC content of 48.01%. In total, we annotated the putative function of 13,134 genes, accounting for 94.97% of the candidate genes. We identified two and 23 candidate genes that are likely involved in the production of mycotoxins zearalenone and trichothecene, respectively. A comparative genomic analysis supported the high quality of the F. equiseti assembly. Our comprehensive analysis of whole-genome sequence will serve as a valuable resource for future studies of expression, regulation, function and evolution of the genes of F. equiseti as well as studies into disease prevention and control.

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