4.6 Review

Landscape of EBV-positive gastric cancer

Related references

Note: Only part of the references are listed.
Article Oncology

ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation

Koji Kase et al.

Summary: In EBV (+) GC, miR-BART11-3p and miR-BART12 regulate ARID1A expression through epigenetic modifications, potentially reducing ARID1A levels, with their expression correlated with ARID1A levels in GC tumors.

CARCINOGENESIS (2021)

Article Multidisciplinary Sciences

PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms

Hiroshi Nakano et al.

Summary: Epstein-Barr virus-positive gastric cancer (EBV (+) GC) exhibits overexpression of PD-L1 through a unique dual mechanism: focal amplification of CD274 or IFN-gamma-mediated signaling via activation of IRF3, correlating with CD8 lymphocyte infiltration and IRF3 signature expression in tumor tissue and infiltrating immune cells.

SCIENTIFIC REPORTS (2021)

Article Gastroenterology & Hepatology

Collision of Epstein-Barr virus-positive and -negative gastric cancer, diagnosed by molecular analysis: a case report

Ken Miyabe et al.

Summary: We report a rare case of gastric carcinoma with co-existence of EBV-positive and EBV-negative components, and conducted various molecular analyses for the first time to elucidate their histogenesis. The patient, an 81-year-old male, underwent systemic chemotherapy followed by total gastrectomy and lymph node dissection. Molecular analysis revealed different gene expression profiles in the EBV-positive and EBV-negative components of the tumor.

BMC GASTROENTEROLOGY (2021)

Review Pathology

Thirty years of Epstein-Barr virus-associated gastric carcinoma

Masashi Fukayama et al.

VIRCHOWS ARCHIV (2020)

Article Biochemistry & Molecular Biology

Epstein-Barr virus miR-BART1-3p suppresses apoptosis and promotes migration of gastric carcinoma cells by targeting DAB2

Kyoungmi Min et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)

Article Biochemistry & Molecular Biology

Epstein-Barr virus miR-BART3-3p promotes tumorigenesis by regulating the senescence pathway in gastric cancer

Jia Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Medicine, Research & Experimental

Mutational landscape of gastric cancer and clinical application of genomic profiling based on target next-generation sequencing

Hui Cai et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2019)

Article Multidisciplinary Sciences

Prognostic role of ARID1A negative expression in gastric cancer

Mai Ashizawa et al.

SCIENTIFIC REPORTS (2019)

Review Microbiology

Epstein-Barr Virus and Innate Immunity: Friends or Foes?

Sonia Jangra et al.

MICROORGANISMS (2019)

Review Biochemistry & Molecular Biology

The Role of Non-coding RNAs in Oncology

Frank J. Slack et al.

Article Oncology

Functional loss of ARID1A is tightly associated with high PD-L1 expression in gastric cancer

Young-Bae Kim et al.

INTERNATIONAL JOURNAL OF CANCER (2019)

Article Biochemistry & Molecular Biology

EBV miR-BART10-3p Promotes Cell Proliferation and Migration by Targeting DKK1

Kyoungmi Min et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)

Article Oncology

Analysis of DNA methylation in cancer: location revisited

Alexander Koch et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

Article Virology

Epstein-Barr Virus MicroRNA miR-BART5-3p Inhibits p53 Expression

Xiang Zheng et al.

JOURNAL OF VIROLOGY (2018)

Review Oncology

Non-coding RNA networks in cancer

Eleni Anastasiadou et al.

NATURE REVIEWS CANCER (2018)

Article Multidisciplinary Sciences

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

Chris T. Williamson et al.

NATURE COMMUNICATIONS (2016)

Article Biochemistry & Molecular Biology

Interferon regulatory factors: at the crossroads of immunity, metabolism, and disease

Guang-Nian Zhao et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)

Article Oncology

Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing

Masataka Takenaka et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2015)

Review Oncology

Update on Epstein-Barr virus and gastric cancer

Aya Shinozaki-Ushiku et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2015)

Review Biochemistry & Molecular Biology

Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma

Margaret L. Gulley

EXPERIMENTAL AND MOLECULAR MEDICINE (2015)

Article Multidisciplinary Sciences

Comprehensive molecular characterization of gastric adenocarcinoma

Adam J. Bass et al.

NATURE (2014)

Article Genetics & Heredity

Pan-cancer patterns of somatic copy number alteration

Travis I. Zack et al.

NATURE GENETICS (2013)

Review Oncology

Epstein-Barr Virus Infection as an Epigenetic Driver of Tumorigenesis

Atsushi Kaneda et al.

CANCER RESEARCH (2012)

Article Microbiology

The Viral and Cellular MicroRNA Targetome in Lymphoblastoid Cell Lines

Rebecca L. Skalsky et al.

PLOS PATHOGENS (2012)

Article Oncology

Downregulation of MicroRNA-200 in EBV-Associated Gastric Carcinoma

Aya Shinozaki et al.

CANCER RESEARCH (2010)

Article Multidisciplinary Sciences

The landscape of somatic copy-number alteration across human cancers

Rameen Beroukhim et al.

NATURE (2010)

Article Immunology

An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival

Elizabeth Yee-Wai Choy et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2008)

Review Medicine, General & Internal

Molecular origins of cancer: Epigenetics in cancer

Manel Esteller

NEW ENGLAND JOURNAL OF MEDICINE (2008)