Journal
FUTURE MICROBIOLOGY
Volume 16, Issue 9, Pages 671-685Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/fmb-2020-0189
Keywords
clinical significance; detection method; GBS; pathogenic mechanism
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Perinatal infection caused by Group B streptococcus poses a serious threat to maternal and infant health, requiring enhanced clinical screening, GBS infection detection, and preventive treatment for mother-infant infections.
Group B streptococcus (GBS) is the main pathogen of perinatal infection. It can lead to adverse pregnancy, maternal infection, premature delivery, abortion, stillbirth and a series of adverse maternal and infant outcomes such as neonatal sepsis, meningitis or pneumonia during delivery. In order to reduce the infection of perinatal pregnant and the adverse pregnancy outcome, more attention should be paid in the clinical practice, screening efforts, universal detection of GBS infection for pregnant women and preventive treatment for the possible mother infant infection. In this study, the biological characteristics, immunophenotype, major pathogenic mechanism, laboratory test methods and clinical significance of GBS are summarized.
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