Related references
Note: Only part of the references are listed.Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities
Marlene F. Schmidt et al.
CELL DEATH AND DIFFERENTIATION (2021)
Knockdown of TRAP1 promotes cisplatin-induced apoptosis by promoting the ROS-dependent mitochondrial dysfunction in lung cancer cells
Xiaowei Zhang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2021)
Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease
Tomohiro Nakamura et al.
SCIENCE (2021)
S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD
Elaine Pirie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Insights Into the Mechanism of Tyrosine Nitration in Preventing β-Amyloid Aggregation in Alzheimer's Disease
Jie Zhao et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2021)
Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling
Uddalak Majumdar et al.
SCIENCE ADVANCES (2021)
Protein Transnitrosylation Signaling Networks Contribute to Inflammaging and Neurodegenerative Disorders
Tomohiro Nakamura et al.
ANTIOXIDANTS & REDOX SIGNALING (2021)
Reducing acetylated tau is neuroprotective in brain injury
Min-Kyoo Shin et al.
CELL (2021)
Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration
Weiwei Yi et al.
CELL REPORTS (2021)
Mitophagy and Neuroprotection
Guofeng Lou et al.
TRENDS IN MOLECULAR MEDICINE (2020)
PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia
Qin Zhao et al.
MOLECULAR CELL (2020)
Nitric Oxide-Dependent Protein Post-Translational Modifications Impair Mitochondrial Function and Metabolism to Contribute to Neurodegenerative Diseases
Tomohiro Nakamura et al.
ANTIOXIDANTS & REDOX SIGNALING (2020)
S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein
Kana Fujikawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Phase Separation and Cytotoxicity of Tau are Modulated by Protein Disulfide Isomerase and S-nitrosylation of this Molecular Chaperone
Kan Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Transnitrosylation Mediated by the Non-canonical Catalase ROG1 Regulates Nitric Oxide Signaling in Plants
Lichao Chen et al.
DEVELOPMENTAL CELL (2020)
TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression
Josiah J. Herzog et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide
Haitham Amal et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Insight into the Folding and Dimerization Mechanisms of the N-Terminal Domain from Human TDP-43
Mirella Vivoli-Vega et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Microautophagy - distinct molecular mechanisms handle cargoes of many sizes
Sebastian Schuck
JOURNAL OF CELL SCIENCE (2020)
The S-nitrosylation of parkin attenuated the ubiquitination of divalent metal transporter 1 in MPP+-treated SH-SY5Y cells
Yanmin Zhong et al.
SCIENTIFIC REPORTS (2020)
Protein S-Nitrosylation: Determinants of Specificity and Enzymatic Regulation of S-Nitrosothiol-Based Signaling
Colin T. Stomberski et al.
ANTIOXIDANTS & REDOX SIGNALING (2019)
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson's Disease Etiopathology
Anna Wilkaniec et al.
MOLECULAR NEUROBIOLOGY (2019)
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
Jacob R. Mann et al.
NEURON (2019)
Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
Peipei Zhang et al.
ELIFE (2019)
Nitration of hIAPP promotes its toxic oligomer formation and exacerbates its toxicity towards INS-1 cells
Jie Zhao et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2019)
Proteome-wide detection of S-nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique
Ruzanna Mnatsakanyan et al.
NATURE COMMUNICATIONS (2019)
Stress granules and neurodegeneration
Benjamin Wolozin et al.
NATURE REVIEWS NEUROSCIENCE (2019)
S-Nitrosylation of CHIP Enhances F508Del-CFTR Maturation
Khalequz Zaman et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)
Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D
Lucie Valek et al.
REDOX BIOLOGY (2019)
Deubiquitylating enzymes and drug discovery: emerging opportunities
Jeanine A. Harrigan et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
S-Nitrosylation of cIAP1 Switches Cancer Cell Fate from TNFα/TNFR1-Mediated Cell Survival to Cell Death
Sabrina Romagny et al.
CANCER RESEARCH (2018)
Biochemistry of Peroxynitrite and Protein Tyrosine Nitration
Gerardo Ferrer-Sueta et al.
CHEMICAL REVIEWS (2018)
A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation
Divya Seth et al.
MOLECULAR CELL (2018)
Evidence against Stable Protein S-Nitrosylation as a Widespread Mechanism of Post-translational Regulation
Kathryn Wolhuter et al.
MOLECULAR CELL (2018)
Neohesperidin Prevents Aβ25-35-Induced Apoptosis in Primary Cultured Hippocampal Neurons by Blocking the S-Nitrosylation of Protein-Disulphide Isomerase
Jijun Wang et al.
NEUROCHEMICAL RESEARCH (2018)
Oxidant/Antioxidant Imbalance in Alzheimer's Disease: Therapeutic and Diagnostic Prospects
Joanna Wojsiat et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
&ITS&IT-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy
Salvatore Rizza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Nitrosylation of GAPDH augments pathological tau acetylation upon exposure to amyloid-β
Tanusree Sen et al.
SCIENCE SIGNALING (2018)
ALS Genes in the Genomic Era and their Implications for FTD
Hung Phuoc Nguyen et al.
TRENDS IN GENETICS (2018)
TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types
Yousra Khalfallah et al.
SCIENTIFIC REPORTS (2018)
Nitrosylation of GAPDH augments pathological tau acetylation upon exposure to amyloid-β
Tanusree Sen et al.
SCIENCE SIGNALING (2018)
Intercellular Spread of Protein Aggregates in Neurodegenerative Disease
Albert A. Davis et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)
The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease
Abdullah Hoter et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
Konstantinos Palikaras et al.
NATURE CELL BIOLOGY (2018)
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
Claudio Soto et al.
NATURE NEUROSCIENCE (2018)
PDI-mediated S-nitrosylation of DRP1 facilitates DRP1-S616 phosphorylation and mitochondrial fission in CA1 neurons
Duk-shin Lee et al.
CELL DEATH & DISEASE (2018)
Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
Silvia Porta et al.
NATURE COMMUNICATIONS (2018)
Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
Koji Abe et al.
LANCET NEUROLOGY (2017)
PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation
Amit Gupta et al.
MOLECULAR CELL (2017)
Dioxins and related environmental contaminants increase TDP-43 levels
Peter E. A. Ash et al.
MOLECULAR NEURODEGENERATION (2017)
Don't keep it in the family
Ammar Al-Chalabi
NATURE (2017)
The HSP90 chaperone machinery
Florian H. Schopf et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models
Chang-Ki Oh et al.
CELL REPORTS (2017)
S-nitrosylation of UCHL1 induces its structural instability and promotes α-synuclein aggregation
Roshan Kumar et al.
SCIENTIFIC REPORTS (2017)
Onset of disorder and protein aggregation due to oxidation-induced intermolecular disulfide bonds: case study of RRM2 domain from TDP-43
Sevastyan O. Rabdano et al.
SCIENTIFIC REPORTS (2017)
Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43A315T ALS/FTD mouse model
Leslie Bargsted et al.
SCIENTIFIC REPORTS (2017)
NOS1 S-nitrosylates PTEN and inhibits autophagy in nasopharyngeal carcinoma cells
Lingqun Zhu et al.
CELL DEATH DISCOVERY (2017)
Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder
Fen-Biao Gao et al.
EMBO JOURNAL (2017)
How are nitrosothiols formed de novo in vivo?
Jack R. Lancaster
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2017)
Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies
Ian R. A. Mackenzie et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Amyloid-β Peptide Nitrotyrosination Stabilizes Oligomers and Enhances NMDAR-Mediated Toxicity
Biuse Guivernau et al.
JOURNAL OF NEUROSCIENCE (2016)
The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
Wenzhang Wang et al.
NATURE MEDICINE (2016)
S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration
Uthpala Seneviratne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Chemoproteomic Strategy to Quantitatively Monitor Transnitrosation Uncovers Functionally Relevant S-Nitrosation Sites on Cathepsin D and HADH2
Yani Zhou et al.
CELL CHEMICAL BIOLOGY (2016)
Post-translational modification of α-synuclein in Parkinson's disease
Paul J. Barrett et al.
BRAIN RESEARCH (2015)
Nitric Oxide Induction of Parkin Translocation in PTEN-induced Putative Kinase 1 (PINK1) Deficiency FUNCTIONAL ROLE OF NEURONAL NITRIC OXIDE SYNTHASE DURING MITOPHAGY
Ji-Young Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
TDP-43 is intercellularly transmitted across axon terminals
Marisa S. Feiler et al.
JOURNAL OF CELL BIOLOGY (2015)
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson's Disease
Alicia M. Pickrell et al.
NEURON (2015)
S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction
Ling Yang et al.
SCIENCE (2015)
Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress
Ryosuke Nakato et al.
SCIENTIFIC REPORTS (2015)
Regulation of autophagy by protein post-translational modification
Willayat Yousuf Wani et al.
LABORATORY INVESTIGATION (2015)
Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases
Haijian Wu et al.
MOLECULAR NEUROBIOLOGY (2015)
Ellagic Acid Mitigates SNO-PDI Induced Aggregation of Parkinsonian Bionnarkers
Parijat Kabiraj et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition
Jie Jia et al.
CELL (2014)
Nitric oxide induces apoptosis and autophagy; autophagy down-regulates NO synthesis in physalin A-treated A375-S2 human melanoma cells
Hao He et al.
FOOD AND CHEMICAL TOXICOLOGY (2014)
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Lesley A. Kane et al.
JOURNAL OF CELL BIOLOGY (2014)
Transnitrosylation from DJ-1 to PTEN Attenuates Neuronal Cell Death in Parkinson's Disease Models
Min Sik Choi et al.
JOURNAL OF NEUROSCIENCE (2014)
Differential Effects of Synaptic and Extrasynaptic NMDA Receptors on Aβ-Induced Nitric Oxide Production in Cerebrocortical Neurons
Elena Molokanova et al.
JOURNAL OF NEUROSCIENCE (2014)
Protein Microarray Characterization of the S-Nitrosoproteome
Yun-Il Lee et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Potential Effect of S-Nitrosylated Protein Disulfide Isomerase on Mutant SOD1 Aggregation and Neuronal Cell Death in Amyotrophic Lateral Sclerosis
Gye Sun Jeon et al.
MOLECULAR NEUROBIOLOGY (2014)
Ubiquitin is phosphorylated by PINK1 to activate parkin
Fumika Koyano et al.
NATURE (2014)
Ubiquitin pathways in neurodegenerative disease
Graham Atkin et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of Functional Effects
Rafael Radi
ACCOUNTS OF CHEMICAL RESEARCH (2013)
Biological nitric oxide signalling: chemistry and terminology
Tassiele A. Heinrich et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity
Valeriy G. Ostapchenko et al.
JOURNAL OF NEUROSCIENCE (2013)
The role of autophagy in neurodegenerative disease
Ralph A. Nixon
NATURE MEDICINE (2013)
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
Shuo-Chien Ling et al.
NEURON (2013)
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
Maria Talantova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nitration of Hsp90 induces cell death
Maria Clara Franco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
S-nitrosylation regulates mitochondrial quality control via activation of parkin
Kentaro Ozawa et al.
SCIENTIFIC REPORTS (2013)
Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains
Takashi Nonaka et al.
CELL REPORTS (2013)
TRAP-1, the mitochondrial Hsp90
Dario C. Altieri et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Measurement of S-Nitrosylation Occupancy in the Myocardium With Cysteine-Reactive Tandem Mass Tags Short Communication
Mark J. Kohr et al.
CIRCULATION RESEARCH (2012)
Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling
Brian C. Smith et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2012)
Nitric oxide synthases: regulation and function
Ulrich Foerstermann et al.
EUROPEAN HEART JOURNAL (2012)
SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI)
Xueping Chen et al.
JOURNAL OF NEUROINFLAMMATION (2012)
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
Iryna Benilova et al.
NATURE NEUROSCIENCE (2012)
The role of nitric oxide on rosuvastatin-mediated S-nitrosylation and translational proteomes in human umbilical vein endothelial cells
Bin Huang et al.
PROTEOME SCIENCE (2012)
Tyrosine Nitration within the Pro line-Rich Region of Tau in Alzheimer's Disease
Juan F. Reyes et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
S-Nitrosylation of Critical Protein Thiols Mediates Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases
Tomohiro Nakamura et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation
Surendra S. Ambegaokar et al.
HUMAN MOLECULAR GENETICS (2011)
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
Karli K. McDonald et al.
HUMAN MOLECULAR GENETICS (2011)
Complex Inhibitory Effects of Nitric Oxide on Autophagy
Sovan Sarkar et al.
MOLECULAR CELL (2011)
Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation
Fanjun Meng et al.
MOLECULAR NEURODEGENERATION (2011)
Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation
Markus P. Kummer et al.
NEURON (2011)
Site-specific and redox-controlled S-nitrosation of thioredoxin
Katherine T. Barglow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)
Naoki Numajiri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by β-amyloid peptide
Jing Qu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Priming of hypoxia-inducible factor by neuronal nitric oxide synthase is essential for adaptive responses to severe anemia
Albert K. Y. Tsui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis
Adam K. Walker et al.
BRAIN (2010)
The IKK complex contributes to the induction of autophagy
Alfredo Criollo et al.
EMBO JOURNAL (2010)
Structural Analysis of Cysteine S-Nitrosylation: A Modified Acid-Based Motif and the Emerging Role of Trans-Nitrosylation
Stefano M. Marino et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) Regulates Its Kinase Activity and Dendrite Growth During Neuronal Development
Peng Zhang et al.
JOURNAL OF NEUROSCIENCE (2010)
Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death
Tomohiro Nakamura et al.
MOLECULAR CELL (2010)
NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration
Young-Don Kwak et al.
MOLECULAR NEURODEGENERATION (2010)
GAPDH mediates nitrosylation of nuclear proteins
Michael D. Kornberg et al.
NATURE CELL BIOLOGY (2010)
A causative link between the structure of aberrant protein oligomers and their toxicity
Silvia Campioni et al.
NATURE CHEMICAL BIOLOGY (2010)
Alpha-synuclein nitration and autophagy response are induced in peripheral blood cells from patients with Parkinson disease
Alessandro Prigione et al.
NEUROSCIENCE LETTERS (2010)
Nitrated α-Synuclein Induces the Loss of Dopaminergic Neurons in the Substantia Nigra of Rats
Zhongwang Yu et al.
PLOS ONE (2010)
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
Liqun Liu-Yesucevitz et al.
PLOS ONE (2010)
Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy
Nadzeya V. Marozkina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation
Paschalis-Thomas Doulias et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Superoxide is the major reactive oxygen species regulating autophagy
Y. Chen et al.
CELL DEATH AND DIFFERENTIATION (2009)
Hsp90 is regulated by a switch point in the C-terminal domain
Marco Retzlaff et al.
EMBO REPORTS (2009)
TDP-43 is recruited to stress granules in conditions of oxidative insult
Claudia Colombrita et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Nitric oxide regulates the 26S proteasome in vascular smooth muscle cells
Muneera R. Kapadia et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2009)
A protein microarray-based analysis of S-nitrosylation
Matthew W. Foster et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury
Dong-Hyung Cho et al.
SCIENCE (2009)
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Masato Hasegawa et al.
ANNALS OF NEUROLOGY (2008)
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
Yongsung Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Regulation of macroautophagy by mTOR and Beclin 1 complexes
Sophie Pattingre et al.
BIOCHIMIE (2008)
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
Matthew J. Winton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Neuroinflammation and oxidation/nitration of α-synuclein linked to dopaminergic neurodegeneration
Hui-Ming Gao et al.
JOURNAL OF NEUROSCIENCE (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
Yongjie Wei et al.
MOLECULAR CELL (2008)
Adapting proteostasis for disease intervention
William E. Balch et al.
SCIENCE (2008)
Superoxide generation from nitric oxide synthases
Yong Xia
ANTIOXIDANTS & REDOX SIGNALING (2007)
IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway
Dung-Fang Lee et al.
CELL (2007)
Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels
Monica Joch et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells
Douglas A. Mitchell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The functions of UCH-L1 and its relation to neurodegenerative diseases
Rieko Setsuie et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
Julia W. Pridgeon et al.
PLOS BIOLOGY (2007)
Intracellular amyloid-β in Alzheimer's disease
Frank M. LaFerla et al.
NATURE REVIEWS NEUROSCIENCE (2007)
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Udai Bhan Pandey et al.
NATURE (2007)
Connecting TNF-α signaling pathways to iNOS expression in a mouse model of Alzheimer's disease:: Relevance for the Behavioral and synaptic deficits induced by amyloid β protein
Rodrigo Medeiros et al.
JOURNAL OF NEUROSCIENCE (2007)
Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
Ganesh M. Shankar et al.
JOURNAL OF NEUROSCIENCE (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation -: A novel antiapoptotic mechanism that suppresses apoptosis
Neelam Azad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis
Ling Tao et al.
CIRCULATION (2006)
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3) K-Akt signalling
Lara Fallon et al.
NATURE CELL BIOLOGY (2006)
Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination
Pithi Chanvorachote et al.
CANCER RESEARCH (2006)
S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
Takashi Uehara et al.
NATURE (2006)
Identification of S-nitrosylated proteins after chronic exposure of colon epithelial cells to deoxycholate
M Dall'Agnol et al.
PROTEOMICS (2006)
Nitric oxide negatively regulates Fas CD95-induced apoptosis through inhibition of ubiquitin-proteasome-mediated degradation of FLICE inhibitory protein
P Chanvorachote et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine
DA Mitchell et al.
NATURE CHEMICAL BIOLOGY (2005)
S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities
A Martínez-Ruiz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Protein S-nitrosylation:: Purview and parameters
DT Hess et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Modulation of neurodegeneration by molecular chaperones
PJ Muchowski et al.
NATURE REVIEWS NEUROSCIENCE (2005)
Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases
J Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine
TS Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nitrosative stress linked to sporadic Parkinson's disease:: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
DD Yao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases
CA Ross et al.
TRENDS IN CELL BIOLOGY (2004)
Protein aggregation and neurodegenerative disease
CA Ross et al.
NATURE MEDICINE (2004)
Structural diversity and functional implications of the eukaryotic TDP gene family
HY Wang et al.
GENOMICS (2004)
Functional consequences of α-synuclein tyrosine nitration -: Diminished binding to lipid vesicles and increased fibril formation
R Hodara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nitric oxide represses inhibitory kB kinase through S-nitrosylation
NL Reynaert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway
S Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M Arrasate et al.
NATURE (2004)
S-nitrosylation of Parkin regulates ubiquitination and compromises Parkin's protective function
KKK Chung et al.
SCIENCE (2004)
The ubiquitin proteasome system in neurodegenerative diseases: Sometimes the chicken, sometimes the egg
A Ciechanover et al.
NEURON (2003)
Nitration of tau protein is linked to neurodegeneration in tauopathies
T Horiguchi et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
α-synuclein is degraded by both autophagy and the proteasome
JL Webb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
E Nisoli et al.
SCIENCE (2003)
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
H Ischiropoulos et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Unfolding the role of protein misfolding in neurodegenerative diseases
C Soto
NATURE REVIEWS NEUROSCIENCE (2003)
cGMP and S-nitrosylation: two routes for modulation of neuronal excitability by NO
GP Ahern et al.
TRENDS IN NEUROSCIENCES (2002)
S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death
ZZ Gu et al.
SCIENCE (2002)
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP
T Gotoh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck et al.
SCIENCE (2002)
Edarabone scavenges nitric oxide
K Satoh et al.
REDOX REPORT (2002)
Expression of A53T mutant but not wild-type α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
L Stefanis et al.
JOURNAL OF NEUROSCIENCE (2001)
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
E Buratti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Nitrosylation: The prototypic redox-based signaling mechanism
JS Stamler et al.
CELL (2001)
Nitric oxide-induced apoptosis in pancreatic β cells is mediated by the endoplasmic reticulum stress pathway
S Oyadomari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease
E Masliah et al.
NEUROLOGY (2001)
Nitric oxide negatively regulates c-Jun N-terminal kinase/stress-activated protein kinase by means of S-nitrosylation
HS Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
BI Giasson et al.
SCIENCE (2000)
Dityrosine cross-linking promotes formation of stable α-synuclein polymers -: Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
JM Souza et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
