4.7 Review

Antiviral activity of fermented foods and their probiotics bacteria towards respiratory and alimentary tracts viruses

Journal

FOOD CONTROL
Volume 127, Issue -, Pages -

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.foodcont.2021.108140

Keywords

Fermented foods; Antiviral; Probiotics; Immune system; Viruses

Funding

  1. Faculty of Food Science and Technology, Universiti Putra Malaysia

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Fermented foods and their probiotics have high antiviral activity, reducing infection risk and promoting rapid recovery, with broad potential against respiratory and digestive viruses. Probiotics demonstrate antiviral activity by activating the immune system, enhancing cytotoxicity, and promoting cytokine production.
The recent COVID-19, a viral outbreak calls for a high demand for non-conventional antiviral agents that can reduce the risk of infections and promote fast recovery. Fermented foods and their probiotics bacteria have recently received increasing interest due to the reported potential of high antiviral activity. Several probiotics strains demonstrated broad range of antiviral activities and different mechanisms of action. This article will review the diversity, health benefits, interaction with immune system and antiviral activity of fermented foods and their probiotics bacteria. In addition, the mechanisms of action will be reviewed to determine the broad range potential antiviral activity against the respiratory and alimentary tracts viruses. The probiotics bacteria and bioactive compounds in fermented foods demonstrated antiviral activities against respiratory and alimentary tracts viruses. The mechanism of action was reported to be due to the stimulation of the immune system function via enhancing natural killers cell toxicity, enhance the production of pro-inflammatory cytokines, and increasing the cytotoxic of T lymphocytes (CD3+, CD16+, CD56+). However, further studies are highly recommended to determine the potential antiviral activity for traditional fermented foods.

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