Journal
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
Volume 38, Issue 9, Pages 1470-1480Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/19440049.2021.1925164
Keywords
3-MCPD esters; 2-MCPD esters; infant formula; exposure assessment
Funding
- Natural Science Foundation of Beijing Municipality [7192086]
- CIFST Food Science and Technology Fund - Abbott Food Nutrition and Safety Special Research Fund [2017-17]
- National Key Research and Development Program of China [2018YFC1603600, 2018YFC1603100]
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A dietary exposure assessment was conducted for 3-and 2-MCPD esters in infant formulas available for consumption in Chinese infants and toddlers aged 0-3 years old. The study found that the overall health risk of Chinese infants and toddlers exposed to 3-MCPD esters was low, but some infants aged 0-6 months with high formula consumption (95th percentile) raised concerns.
The presence of 3-monochloropropane-1,2-diol (3-MCPD) esters and 2-MCPD esters in infant formulas have raised a number of food safety concerns. Here, a dietary exposure assessment was conducted for 3-and 2-MCPD esters in infant formulas available for consumption in Chinese infant and toddlers aged 0-3 years old. This work presents the occurrence data for 3-and 2-MCPD ester in 874 infant formulas purchased in China between 2015 and 2017. The concentrations of 3-MCPD esters ranged from ND to 1.469 mg/kg, with concentrations of 2-MCPD esters ranging from ND to 0.218 mg/kg. The LODs of 3-and 2-MCPD esters were 0.027-0.074 mg/kg. The mean exposures of infants and toddlers to 3-MCPD esters from formulas were lower than the tolerable daily intake (TDI, 2 mu g/kg bw/day, established by EFSA), while high exposures (95th percentile) to 3-MCPD esters ranged from 0.907 to 2.520 mu g/kg bw/day. On the whole, the health risk of Chinese infant and toddlers exposed to 3-MCPD esters was low, but the health risk of some infants aged 0-6 months with high formula consumption (95th percentile) raises some concern.
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