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Timing of Decompressive Surgery of Spinal Cord after Traumatic Spinal Cord Injury: An Evidence-Based Examination of Pre-Clinical and Clinical Studies
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Apolipoprotein E epsilon 4 allele and outcomes of traumatic spinal cord injury in a Chinese Han population
ChongYi Sun et al.
MOLECULAR BIOLOGY REPORTS (2011)
Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway
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Bahareh Ajami et al.
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Repertoire of microglial and macrophage responses after spinal cord injury
Samuel David et al.
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Emerging Concepts in Myeloid Cell Biology after Spinal Cord Injury
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Enrichment of Sialylated IgG by Lectin Fractionation Does Not Enhance the Efficacy of Immunoglobulin G in a Murine Model of Immune Thrombocytopenia
Theresa Guhr et al.
PLOS ONE (2011)
IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes
Jean-Francois Seite et al.
BLOOD (2010)
Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury
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BRAIN (2010)
Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment
Kevin D. Beck et al.
BRAIN (2010)
Lack of neuroprotective effects of simvastatin and minocycline in a model of cervical spinal cord injury
Jae H. T. Lee et al.
EXPERIMENTAL NEUROLOGY (2010)
Efficacy of the coadministration of granulocyte colony-stimulating factor and stem cell factor in the activation of intrinsic cells after spinal cord injury in mice
Takahiro Osada et al.
JOURNAL OF NEUROSURGERY-SPINE (2010)
Hypothermia Prior to Decompression: Buying Time for Treatment of Acute Spinal Cord Injury
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Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
Simon Mendez-Ferrer et al.
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Involvement of Fc Receptors in Disorders of the Central Nervous System
Eitan Okun et al.
NEUROMOLECULAR MEDICINE (2010)
Clinical Outcomes Using Modest Intravascular Hypothermia After Acute Cervical Spinal Cord Injury
Allan D. Levi et al.
NEUROSURGERY (2010)
B cells and autoantibodies: complex roles in CNS injury
Daniel P. Ankeny et al.
TRENDS IN IMMUNOLOGY (2010)
The Long-Term Effects of Mild to Moderate Hypothermia on Gray and White Matter Injury After Spinal Cord Ischemia in Rats
Toshinori Horiuchi et al.
ANESTHESIA AND ANALGESIA (2009)
Ex vivo-expanded autologous bone marrow-derived mesenchymal stromal cells in human spinal cord injury/paraplegia: a pilot clinical study
Rakhi Pal et al.
CYTOTHERAPY (2009)
Spinal cord injury and neural repair: focus on neuroregenerative approaches for spinal cord injury
Darryl C. Baptiste et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2009)
B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice
Daniel P. Ankeny et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Systemic Hypothermia Improves Histological and Functional Outcome After Cervical Spinal Cord Contusion in Rats
Thomas Pang Lo et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
Stress hormones collaborate to induce lymphocyte apoptosis after high level spinal cord injury
Kurt M. Lucin et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Depletion of Ly6G/Gr-1 Leukocytes after Spinal Cord Injury in Mice Alters Wound Healing and Worsens Neurological Outcome
David P. Stirling et al.
JOURNAL OF NEUROSCIENCE (2009)
Macrophages Promote Axon Regeneration with Concurrent Neurotoxicity
John C. Gensel et al.
JOURNAL OF NEUROSCIENCE (2009)
Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
Kristina A. Kigerl et al.
JOURNAL OF NEUROSCIENCE (2009)
NEUROPROTECTION IN STROKE BY COMPLEMENT INHIBITION AND IMMUNOGLOBULIN THERAPY
T. V. Arumugam et al.
NEUROSCIENCE (2009)
MECHANISMS AND IMPLICATIONS OF ADAPTIVE IMMUNE RESPONSES AFTER TRAUMATIC SPINAL CORD INJURY
D. P. Ankeny et al.
NEUROSCIENCE (2009)
IMMUNE DEPRESSION SYNDROME FOLLOWING HUMAN SPINAL CORD INJURY (SCI): A PILOT STUDY
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Spinal cord injury: plasticity, regeneration and the challenge of translational drug development
Armin Blesch et al.
TRENDS IN NEUROSCIENCES (2009)
Autoimmune T cell responses in the central nervous system
Joan Goverman
NATURE REVIEWS IMMUNOLOGY (2009)
Anti-inflammatory actions of intravenous immunoglobulin
Falk Nimmerjahn et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
A re-assessment of minocycline as a neuroprotective agent in a rat spinal cord contusion model
Alberto Pinzon et al.
BRAIN RESEARCH (2008)
A perivascular origin for mesenchymal stem cells in multiple human organs
Mihaela Crisan et al.
CELL STEM CELL (2008)
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
Dustin J. Donnelly et al.
EXPERIMENTAL NEUROLOGY (2008)
Emerging drugs for spinal cord injury
Darryl C. Baptiste et al.
EXPERT OPINION ON EMERGING DRUGS (2008)
STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury
Julia E. Herrmann et al.
JOURNAL OF NEUROSCIENCE (2008)
Apolipoprotein E epsilon-4 allele and outcomes of traumatic spinal cord injury
Amitabh Jha et al.
JOURNAL OF SPINAL CORD MEDICINE (2008)
Liver Kupffer cells control the magnitude of the inflammatory response in the injured brain and spinal cord
Sandra J. Campbell et al.
NEUROPHARMACOLOGY (2008)
Identification of a receptor required for the anti-inflammatory activity of IVIG
Robert M. Anthony et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Altered innate immunity following spinal cord injury
D. I. Campagnolo et al.
SPINAL CORD (2008)
Microglia inhibition is a target of mild hypothermic treatment after the spinal cord injury
T. Morino et al.
SPINAL CORD (2008)
Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice
Jean M. Daley et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-Mediated intraspinal macrophage activation
David L. Schonberg et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Cell biology and clinical promise of G-CSF: immunomodulation and neuroprotection
Bao-Guo Xiao et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2007)
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death
Thiruma V. Arumugam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Autonomic innervation and regulation of the immune system (1987-2007)
Dwight M. Nance et al.
BRAIN BEHAVIOR AND IMMUNITY (2007)
Curiosity and cure: Translational research strategies for neural repair-mediated rehabilitation
Bruce H. Dobkin
DEVELOPMENTAL NEUROBIOLOGY (2007)
Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury
Tae Y. Yune et al.
JOURNAL OF NEUROSCIENCE (2007)
Granulocyte colony-stimulating factor (G-CSF) mobilizes bone marrow-derived cells into injured spinal cord and promotes functional recovery after compression-induced spinal cord injury in mice
Masao Koda et al.
BRAIN RESEARCH (2007)
Central nervous system and non-central nervous system antigen vaccines exacerbate neuropathology caused by nerve injury
Daniel P. Ankeny et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Spinal cord injury-induced immune depression syndrome (SCI-IDS)
Tino Riegger et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials
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SPINAL CORD (2007)
Contusion, dislocation, and distraction: primary hemorrhage and membrane permeability in distinct mechanisms of spinal cord injury
Anthony M. Choo et al.
JOURNAL OF NEUROSURGERY-SPINE (2007)
Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation
Kurt M. Lucin et al.
EXPERIMENTAL NEUROLOGY (2007)
The cellular inflammatory response in human spinal cords after injury
Jennifer C. Fleming et al.
BRAIN (2006)
Reversal of immune thrombocytopenia in mice by cross-linking human immunoglobulin G with a high-affinity monoclonal antibody
Renee Bazin et al.
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Clinical canine spinal cord injury provides an opportunity to examine the issues in translating laboratory techniques into practical therapy
N. D. Jeffery et al.
SPINAL CORD (2006)
A therapeutic time window for anti-CD11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following severe spinal cord injury
David S. Ditor et al.
JOURNAL OF NEUROSURGERY-SPINE (2006)
Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation
Yoshikatsu Kaneko et al.
SCIENCE (2006)
Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury
Barry W. Festoff et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Augmented locomotor recovery after spinal cord injury in the athymic nude rat
Jason R. Potas et al.
JOURNAL OF NEUROTRAUMA (2006)
The therapeutic potential of neural stem cells
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NATURE REVIEWS NEUROSCIENCE (2006)
Pharmacological approaches to repair the injured spinal cord
DC Baptiste et al.
JOURNAL OF NEUROTRAUMA (2006)
Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury
KA Kigerl et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2006)
Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow
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CELL (2006)
Characteristics of bone marrow cells under conditions of impaired innervation in patients with spinal trauma
E. R. Chernykh et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2006)
Tissue displacement and impact force are important contributors to outcome after spinal cor contusion injury
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EXPERIMENTAL NEUROLOGY (2005)
Central nervous system injury-induced immune deficiency syndrome
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NATURE REVIEWS NEUROSCIENCE (2005)
Methylprednisolone inhibits production of interleukin-1β and interleukin-6 in the spinal cord following compression injury in rats
ES Fu et al.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY (2005)
Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression
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NEUROBIOLOGY OF DISEASE (2005)
Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function
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JOURNAL OF NEUROSCIENCE (2004)
Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats
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JOURNAL OF NEUROSCIENCE (2004)
Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
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JOURNAL OF NEUROSCIENCE (2004)
Reactive astrocytes protect tissue and preserve function after spinal cord injury
JR Faulkner et al.
JOURNAL OF NEUROSCIENCE (2004)
Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats
F Bao et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Regeneration beyond the glial scar
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NATURE REVIEWS NEUROSCIENCE (2004)
Initiation of immune responses in brain is promoted by local dendritic cells
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JOURNAL OF IMMUNOLOGY (2004)
Stress-induced suppression of in vivo splenic cytokine production in the rat by neural and hormonal mechanisms
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BRAIN BEHAVIOR AND IMMUNITY (2004)
Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan
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JOURNAL OF NEUROSCIENCE (2003)
Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis
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MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice
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JOURNAL OF NEUROSCIENCE (2003)
Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat
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JOURNAL OF NEUROTRAUMA (2003)
Rats and mice exhibit distinct inflammatory reactions after spinal cord injury
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JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
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NATURE (2003)
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MC Dalakas
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Immunomodulatory action of intravenous immunoglobulin
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IMMUNOLOGY (2002)
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
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Genetic influences on secondary degeneration and wound healing following spinal cord injury in various strains of mice
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Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo
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Elevated serum titers of proinflammatory cytokines and CNS autoantibodies in patients with chronic spinal cord injury
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SPINE (2001)
Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing
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Alterations in immune cell phenotype and function after experimental spinal cord injury
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Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord
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Production of neurotrophins by activated T cells: Implications for neuroprotective autoimmunity
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Methylprednisolone for acute spinal cord injury: an inappropriate standard of care
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