4.5 Article

The dynamic changes of Nrf2 mediated oxidative stress, DNA damage and base excision repair in testis of rats during aging

Related references

Note: Only part of the references are listed.
Review Dermatology

Principles of the Molecular and Cellular Mechanisms of Aging

Paulo F. L. da Silva et al.

Summary: Aging is characterized by progressive functional decline and increased mortality, driven by cellular damage accumulation, low-grade inflammation, and disrupted intercellular communication and homeostasis. This process is influenced by epigenetic changes, gene expression dysregulation, and altered endocrine signaling, making age the main risk factor for age-associated diseases.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2021)

Article Multidisciplinary Sciences

Insights into replicative senescence of human testicular peritubular cells

Nina Schmid et al.

SCIENTIFIC REPORTS (2019)

Review Developmental Biology

Steroidogenesis in Leydig cells: effects of aging and environmental factors

Yiyan Wang et al.

REPRODUCTION (2017)

Article Reproductive Biology

Effects of Aging and Oxidative Stress on Spermatozoa of Superoxide-Dismutase 1-and Catalase-Null Mice

Johanna S. Selvaratnam et al.

BIOLOGY OF REPRODUCTION (2016)

Article Geriatrics & Gerontology

Overexpression of catalase in mice reduces age-related oxidative stress and maintains sperm production

Johanna Selvaratnam et al.

EXPERIMENTAL GERONTOLOGY (2016)

Review Toxicology

The role of DNA damage responses in p53 biology

Daniel Speidel

ARCHIVES OF TOXICOLOGY (2015)

Article Cell Biology

Knockout of the transcription factor Nrf2: Effects on testosterone production by aging mouse Leydig cells

Haolin Chen et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)

Article Biochemistry & Molecular Biology

Apurinic/apyrimidinic endonuclease 1 on aging-associated deteriorations in rat kidneys

In Youb Chang et al.

FREE RADICAL RESEARCH (2015)

Review Biochemistry & Molecular Biology

Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress

Shan Yan et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2014)

Article Urology & Nephrology

Quantitative histological analysis and ultrastructure of the aging human testis

Huan Jiang et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2014)

Article Andrology

Alterations in the estrogen environment of the testis contribute to declining sperm production in aging rats

Michael Clarke et al.

SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE (2014)

Review Endocrinology & Metabolism

Roles of reactive oxygen species in the spermatogenesis regulation

Giulia Guerriero et al.

FRONTIERS IN ENDOCRINOLOGY (2014)

Article Reproductive Biology

Aging Results in Molecular Changes in an Enriched Population of Undifferentiated Rat Spermatogonia

Catriona Paul et al.

BIOLOGY OF REPRODUCTION (2013)

Review Biochemistry & Molecular Biology

The Hallmarks of Aging

Carlos Lopez-Otin et al.

Review Urology & Nephrology

Ageing of the male germ line

Catriona Paul et al.

NATURE REVIEWS UROLOGY (2013)

Article Cell Biology

Age-Dependent Accumulation of 8-Oxoguanine in the DNA and RNA in Various Rat Tissues

Ben Nie et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Article Reproductive Biology

In Vivo and In Vitro Aging Is Detrimental to Mouse Spermatogonial Stem Cell Function

Jonathan A. Schmidt et al.

BIOLOGY OF REPRODUCTION (2011)

Article Geriatrics & Gerontology

Effect of caloric restriction on base-excision repair (BER) in the aging rat brain

Glen E. Kisby et al.

EXPERIMENTAL GERONTOLOGY (2010)

Article Biochemistry & Molecular Biology

Knockout of the transcription factor NRF2 disrupts spermatogenesis in an age-dependent manner

Brooke N. Nakamura et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Cell Biology

The aging male hypothalamic-pituitary-gonadal axis: Pulsatility and feedback

Johannes D. Veldhuis et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)

Article Food Science & Technology

Lead induces oxidative stress, DNA damage and alteration of p53, Bax and Bcl-2 expressions in mice

Jin Xu et al.

FOOD AND CHEMICAL TOXICOLOGY (2008)

Reprint Cell Biology

Antioxidant systems and oxidative stress in the testes (Reprinted from Molecular Mechanisms in Spermatogenesis, 2007)

R. John Aitken et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2008)

Article Cell & Tissue Engineering

Effects of aging and niche microenvironment on spermatogonial stem cell self-renewal

Buom-Yong Ryu et al.

STEM CELLS (2006)

Article Biochemistry & Molecular Biology

Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense systems in testicular rat Leydig cells

LC Cao et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2004)

Article Biotechnology & Applied Microbiology

Attenuation of DNA polymerase β-dependent base excision repair and increased DMS-induced mutagenicity in aged mice

DC Cabelof et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2002)

Review Medicine, Research & Experimental

Age and organ dependent spontaneous generation of nuclear 8-hydroxydeoxyguanosine in male Fischer 344 rats

D Nakae et al.

LABORATORY INVESTIGATION (2000)