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FEBS LETTERS (2008)
Activity of superoxide dismutase isoenzymes in lens epithelial cells derived from different types of age-related cataract
Sankaranarayanan Rajkumar et al.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2008)
Estrogen Protects against Radiation-Induced Cataractogenesis
Joseph R. Dynlacht et al.
RADIATION RESEARCH (2008)
Free and bound water in normal and cataractous human lenses
Karl R. Heys et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Effect of thioltransferase (glutaredoxin) deletion on cellular sensitivity to oxidative stress and cell proliferation in lens epithelial cells of thioltransferase knockout mouse
Stefan Loefgren et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase
Marilyn M. Lall et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Arsenic trioxide initiates ER stress responses, perturbs calcium signalling and promotes apoptosis in human lens epithelial cells
Hong Zhang et al.
EXPERIMENTAL EYE RESEARCH (2007)
Taurine prevents oxidative damage of high glucose-induced cataractogenesis in isolated rat lenses
Hee-Young Son et al.
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY (2007)
Regulation of the bioavailability of thioredoxin in the lens by a specific thioredoxin-binding protein (TBP-2)
Narnal P. M. Liyanage et al.
EXPERIMENTAL EYE RESEARCH (2007)
Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress
Molly M. Gallogly et al.
CURRENT OPINION IN PHARMACOLOGY (2007)
Cell death modalities: classification and pathophysiological implications
L. Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2007)
Endoplasmic reticulum stress: Signaling the unfolded protein response
Elida Lai et al.
PHYSIOLOGY (2007)
Low molecular weight protein tyrosine phosphatase (LMW-PTP) and its possible physiological functions of redox signaling in the eye lens
Kuiyi Xing et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2007)
Reactive oxygen species mediates the apoptosis induced by transforming growth factor β2 in human lens epithelial cells
Ke Yao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Inhibition of nuclear factor-kappa B activation attenuates hydrogen peroxide-induced cytotoxicity in human lens epithelial cells
Xue-Hai Jin et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2007)
Effect of magnesium deficiency on intracellular ATP levels in human lens epithelial cells
Noriaki Nagai et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2007)
The lens circulation
Richard T. Mathias et al.
JOURNAL OF MEMBRANE BIOLOGY (2007)
Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferase
Hong Yan et al.
CURRENT EYE RESEARCH (2007)
Parthenolide protects human lens epithelial cells from oxidative stress-induced apoptosis via inhibition of activation of caspase-3 and caspase-9
Hangping Yao et al.
CELL RESEARCH (2007)
Lens cells: More than meets the eye
Frederique M. D. Tholozan et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model
Xingjun Fan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Silencing of the methionine sulfoxide reductase A gene results in loss of mitochondrial membrane potential and increased ROS production in human lens cells
Maria A. Marchetti et al.
EXPERIMENTAL EYE RESEARCH (2006)
Oxidation-induced changes in human lens epithelial cells - 1. Phospholipids
Li Huang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Thioredoxin induced antioxidant gene expressions in human lens epithelial cells
Svitlana Yegorova et al.
EXPERIMENTAL EYE RESEARCH (2006)
Role of the unfolded protein response (UPR) in cataract formation
Kengo Ikesugi et al.
EXPERIMENTAL EYE RESEARCH (2006)
Levels of zinc, iron, and copper in patients with pseudoexfoliative cataract
T. Cumurcu et al.
EUROPEAN JOURNAL OF OPHTHALMOLOGY (2006)
Oxygen distribution in the rabbit eye and oxygen consumption by the lens
YB Shui et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
Development- and age-associated expression pattern of peroxiredoxin 6, and its regulation in murine ocular lens
E Kubo et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2006)
Oxidation, antioxidants and cataract formation: a literature review
David L. Williams
VETERINARY OPHTHALMOLOGY (2006)
Assessment of aqueous humor zinc status in human age-related cataract
I Nourmohammadi et al.
ANNALS OF NUTRITION AND METABOLISM (2006)
Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of age-related cortical cataract in mice
W Pendergrass et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Telomeres and telomerase biology in vertebrates: Progress towards a non-human model for replicative senescence and ageing
T Davis et al.
BIOGERONTOLOGY (2005)
Induction of thioltransferase and thioredoxin/thioredoxin reductase systems in cultured porcine lenses under oxidative stress
S Moon et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Impaired homeostasis and phenotypic abnormalities in Prdx6-/- mice lens epithelial cells by reactive oxygen species:: increased expression and activation of TGFβ
N Fatma et al.
CELL DEATH AND DIFFERENTIATION (2005)
Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling
SG Rhee et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Growth factor receptor signalling in human lens cells: role of the calcium store
LX Wang et al.
EXPERIMENTAL EYE RESEARCH (2005)
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance
RA Miller et al.
AGING CELL (2005)
Methionine sulfoxide Reductases B1, B2, and B3 are present in the human lens and confer oxidative stress resistance to lens cells
MA Marchetti et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Age-related nuclear cataract - oxidation is the key
RJW Truscott
EXPERIMENTAL EYE RESEARCH (2005)
Lens epithelial apoptosis and cell proliferation in human age-related cortical cataract
A Charakidas et al.
EUROPEAN JOURNAL OF OPHTHALMOLOGY (2005)
Mitochondria, oxidants, and aging
RS Balaban et al.
CELL (2005)
Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress
S Choudhary et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Vitrectomy surgery increases oxygen exposure to the lens: A possible mechanism for nuclear cataract formation.
NM Holekamp et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2005)
Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation
DWC Li et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Connections between connexins, calcium, and cataracts in the lens
JY Gao et al.
JOURNAL OF GENERAL PHYSIOLOGY (2004)
The pathophysiology of mitochondrial cell death
DR Green et al.
SCIENCE (2004)
Age-dependent protein modifications and declining proteasome activity in the human lens
G Viteri et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Dietary caloric restriction may delay the development of cataract by attenuating the oxidative stress in the lenses of Brown Norway rats
KY Wang et al.
EXPERIMENTAL EYE RESEARCH (2004)
Methionine sulfoxide reductase A is important for lens cell viability and resistance to oxidative stress
M Kantorow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Ageing and vision: structure, stability and function of lens crystallins
H Bloemendal et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2004)
Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes
B Herrera et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Apoptotic and necrotic mechanisms of stress-induced human lens epithelial cell death
AC Long et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2004)
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
PS Brookes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Possible physiological function of thioltransferase in cells
KY Xing et al.
FASEB JOURNAL (2003)
Redox regulation in the lens
MF Lou
PROGRESS IN RETINAL AND EYE RESEARCH (2003)
Lycopene attenuates oxidative stress induced experimental cataract development: An in vitro and in vivo study
SK Gupta et al.
NUTRITION (2003)
Human lens thioredoxin: Molecular cloning and functional characterization
S Yegorova et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Oxidative damage to human lens epithelial cells in culture: Estrogen protection of mitochondrial potential, ATP, and cell viability
XF Wang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Increased levels of advanced glycation end products in human cataractous lenses
S Franke et al.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2003)
Vitamin C and vitamin E restore the resistance of GSH-depleted lens cells to H2O2
F Shang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Activation of metallothioneins and α-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses
JR Hawse et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Aldose reductase mediates cytotoxic signals of hyperglycemia and TNF-α in human lens epithelial cells
KV Ramana et al.
FASEB JOURNAL (2002)
Deamidation, but not truncation, decreases the urea stability of a lens structural protein, βB1-crystallin
YH Kim et al.
BIOCHEMISTRY (2002)
Lens superoxide dismutase and catalase activities in diabetic cataract
B Özmen et al.
CLINICAL BIOCHEMISTRY (2002)
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture
JE Contreras et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Effect of H2O2 on human lens epithelial cells and the possible mechanism for oxidative damage repair by thioltransferase
KY Xing et al.
EXPERIMENTAL EYE RESEARCH (2002)
H2O2-mediated oxidative stress activates NF-κB in lens epithelial cells
EJ Dudek et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2
VN Gladyshev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Age-related telomere shortening occurs in lens epithelium from old rats and is slowed by caloric restriction
WR Pendergrass et al.
EXPERIMENTAL EYE RESEARCH (2001)
Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms
M Lundberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor β in fetal hepatocytes
B Herrera et al.
FASEB JOURNAL (2001)
Regulation of cell function by methionine oxidation and reduction
T Hoshi et al.
JOURNAL OF PHYSIOLOGY-LONDON (2001)
Distribution of ferritin and redox-active transition metals in normal and cataractous human lenses
B Garner et al.
EXPERIMENTAL EYE RESEARCH (2000)
Modulation of lens glycolytic pathway by thioltransferase
FY Qiao et al.
EXPERIMENTAL EYE RESEARCH (2000)
Glutathione: A vital lens antioxidant
FJ Giblin
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2000)
Growth factor receptor gene and protein expressions in the human lens
DK Bhuyan et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2000)
Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice
GP Fan et al.
FEBS LETTERS (2000)
Lens epithelium-derived growth factor: Effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts
DP Singh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)