Journal
EXERCISE AND SPORT SCIENCES REVIEWS
Volume 49, Issue 4, Pages 284-290Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000270
Keywords
satellite cells; capillarization; endothelial cells; skeletal muscle; regeneration
Categories
Funding
- Canadian Institutes of Health Research Postdoctoral Fellowship
- Netherlands Organization for Scientific Research (NWO) -Veni research grant [91619008]
- Natural Sciences and Engineering Research Council of Canada [1455843]
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Satellite cells are crucial for skeletal muscle regeneration, repair, and adaptation, their activities are influenced by interactions with muscle-resident endothelial cells. The microvascular network between muscle fibers plays a critical role in satellite cell function, and exercise-induced angiogenesis can help mitigate the decline in satellite cell function with age.
Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.
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