Journal
EUROSURVEILLANCE
Volume 26, Issue 30, Pages -Publisher
EUR CENTRE DIS PREVENTION & CONTROL
DOI: 10.2807/1560-7917.ES.2021.26.30.2100673
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Funding
- Bavarian State Ministry of Science and the Arts
- Ludwig-Maximilians-Universitat Munich
- German Ministry for Education and Research [01KI20271]
- Medical Biodefense Research Program of the Bundeswehr Medical Service
- University Hospital
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In February 2021, a breakthrough infection of the SARS-CoV-2 B.1.351 variant occurred in a fully Comirnaty vaccinated healthcare worker, which was then transmitted to their unvaccinated spouse. Sequencing revealed an identical virus in both spouses, with all nine single nucleotide polymorphisms typical for B.1.351. To date, no transmission of any variant of SARS-CoV-2 from a fully vaccinated person has been documented.
A breakthrough infection occurred in a fully Comirnaty (BNT162b2) vaccinated healthcare worker with high levels of neutralising antibodies with the SARS-CoV-2 B.1.351 (Beta) variant in February 2021. The infection was subsequently transmitted to their unvaccinated spouse. Sequencing revealed an identical virus in both spouses, with a match of all nine single nucleotide polymorphisms typical for B.1.351. To the best of our knowledge, no transmission of any variant of SARS-CoV-2 from a fully vaccinated person has been described before.
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