4.5 Article

Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021

Journal

EUROSURVEILLANCE
Volume 26, Issue 37, Pages -

Publisher

EUR CENTRE DIS PREVENTION & CONTROL
DOI: 10.2807/1560-7917.ES.2021.26.37.2100800

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Funding

  1. European Commission
  2. Dutch Ministry of Health, Welfare and Sport
  3. Ministry of Economy, Innovation, Digitalisation and Energy of the German Federal State of North Rhine-Westphalia
  4. Ministry for National and European Affairs and Regional Development of Lower Saxony within the INTERREG V A [202085]

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This study describes two false-negative results in the detection of meticillin-resistant Staphylococcus aureus (MRSA) of sequence type 398 and spa type t011 using the Cepheid Xpert MRSA NxG assay, indicating that this MRSA strain may have been spreading in the northern Netherlands for some time and could have disseminated to other regions.
We describe two false-negative results in the detection of meticillin-resistant Staphylococcus aureus (MRSA) of sequence type 398 and spa type t011 using the Cepheid Xpert MRSA NxG assay. The isolates were recovered in late February and early March 2021 from two patients in different hospitals in the northern Netherlands. Variations between the two isolate genomes indicate that this MRSA strain might have been spreading for some time and could have disseminated to other regions of the Netherlands and other European countries.

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