4.5 Article

Soticlestat, a novel cholesterol 24-hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice

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Summary: Soticlestat is a selective inhibitor of cholesterol 24-hydroxylase, developed for the treatment of rare developmental and epileptic encephalopathies. In a first-in-human study, it was well tolerated and rapidly absorbed when administered as an oral solution.

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