4.7 Article

Umbelliferone alleviates hepatic ischemia/reperfusion-induced oxidative stress injury via targeting Keap-1/Nrf-2/ARE and TLR4/NF-κB-p65 signaling pathway

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

The Impact of Royal Jelly against Hepatic Ischemia/Reperfusion-Induced Hepatocyte Damage in Rats: The Role of Cytoglobin, Nrf-2/HO-1/COX-4, and P38-MAPK/NF-κB-p65/TNF-α Signaling Pathways

Fares E. M. Ali et al.

Summary: The study demonstrates that royal jelly possesses hepatoprotective effects against hepatic ischemia/reperfusion injury by modulating cytoglobin, Nrf-2/HO-1/COX-4, and P38-MAPK/NF-κB-p65/TNF-α signaling pathways.

CURRENT MOLECULAR PHARMACOLOGY (2021)

Article Biochemistry & Molecular Biology

Nephroprotective effect of umbelliferone against cisplatin-induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO-3, and NF-kappa B-p65 signaling pathways

Fares E. M. Ali et al.

Summary: The study showed that UMB can protect rats against Cis-induced nephrotoxicity while enhancing its antitumor activity. UMB treatment improved renal function biomarkers, cytokines, and oxidant/antioxidant levels, suggesting its potential as an adjuvant therapy in Cis chemotherapeutic protocols.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021)

Article Anatomy & Morphology

Perindopril Ameliorates Hepatic Ischemia Reperfusion Injury Via Regulation of NF-κB-p65/TLR-4, JAK1/STAT-3, Nrf-2, and PI3K/Akt/mTOR Signaling Pathways

Esam O. Kamel et al.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases

J. Catharina Duvigneau et al.

CYTOKINE (2019)

Review Pharmacology & Pharmacy

Protective effects of curcumin against ischemia-reperfusion injury in the liver

Kowsar Bavarsad et al.

PHARMACOLOGICAL RESEARCH (2019)

Review Pharmacology & Pharmacy

The Role of Nrf2 in Liver Disease: Novel Molecular Mechanisms and Therapeutic Approaches

Dongwei Xu et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Biochemistry & Molecular Biology

TNIP1 alleviates hepatic ischemia/reperfusion injury via the TLR2-Myd88 pathway

Yong Zhang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Medicine, Research & Experimental

Tauroursodeoxycholic acid alleviates hepatic ischemia reperfusion injury by suppressing the function of Kupffer cells in mice

Xuesong Xu et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Biochemistry & Molecular Biology

Plants and Surgery: The Protective Effects of Thymoquinone on Hepatic Injury-A Systematic Review of In Vivo Studies

Aysun Tekbas et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Medicine, Research & Experimental

Monomethyl fumarate alleviates sepsis-induced hepatic dysfunction by regulating TLR-4/NF-kappa B signalling pathway

Armin Azadkhah Shalmani et al.

LIFE SCIENCES (2018)

Article Cell Biology

Vildagliptin Attenuates Hepatic Ischemia/Reperfusion Injury via the TLR4/NF-κB Signaling Pathway

Iman O. Sherif et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

Article Biochemistry & Molecular Biology

Hepatoprotective effects of limb ischemic post-conditioning in hepatic ischemic rat model and liver cancer patients via PI3K/ERK pathways

Yanfeng Gao et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2018)

Review Pharmacology & Pharmacy

Natural Active Compounds from Plant Food and Chinese Herbal Medicine for Nonalcoholic Fatty Liver Disease

Qian Liu et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

Article Medicine, Research & Experimental

Protective effects of crocin and zinc sulfate on hepatic ischemia-reperfusion injury in rats: a comparative experimental model study

Seyyed Ali Mard et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Article Cell Biology

Umbelliferone and esculetin protect against N-nitrosodiethylamine- induced hepatotoxicity in rats

Sudhakar Raja Subramaniam et al.

CELL BIOLOGY INTERNATIONAL (2016)

Article Surgery

Nrf2 Activation Protects the Liver From Ischemia/Reperfusion Injury in Mice

Kazuhiro Kudoh et al.

ANNALS OF SURGERY (2014)

Review Gastroenterology & Hepatology

Mechanisms of hepatic ischemia-reperfusion injury and protective effects of nitric oxide

Lian-Yue Guan et al.

WORLD JOURNAL OF GASTROINTESTINAL SURGERY (2014)

Review Biophysics

Molecular Basis of NF-kappa B Signaling

Johanna Napetschnig et al.

ANNUAL REVIEW OF BIOPHYSICS, VOL 42 (2013)

Review Pharmacology & Pharmacy

Role of Nrf2 in Oxidative Stress and Toxicity

Qiang Ma

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)

Review Cell Biology

Role of the Nrf2-ARE Pathway in Liver Diseases

Sang Mi Shin et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Review Pharmacology & Pharmacy

Nrf2: A Potential Target for New Therapeutics in Liver Disease

A. M. Bataille et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)

Article Biochemistry & Molecular Biology

TNF-α Expression in Schwann Cells is Induced by LPS and NF-κB-Dependent Pathways

Yongwei Qin et al.

NEUROCHEMICAL RESEARCH (2012)

Article Cell Biology

The Nuclear Factor NF-κB Pathway in Inflammation

Toby Lawrence

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)

Article Pharmacology & Pharmacy

Umbelliferone and Esculetin: Inhibitors or Substrates for Polyphenol Oxidases?

Francesca Sollai et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2008)

Article Gastroenterology & Hepatology

Expression of macrophage inflammatory protein-1α in Kupffer cells following liver ischemia or reperfusion injury in rats

Wei Ma et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2006)