4.7 Article

US EPA: Is there room to open a new window for evaluating potential sub-threshold effects and ecological risks?

Journal

ENVIRONMENTAL POLLUTION
Volume 284, Issue -, Pages -

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2021.117372

Keywords

Dose-response relationship; Ecological health; Environmental pollution; Hormesis; Pivotal regulatory science; Risk assessment

Funding

  1. Startup Foundation for Introducing Talent of Nanjing University of Information Science and Technology, Nanjing, China [003080]
  2. U.S. Air Force [AFOSR FA9550-13-1-0047]
  3. ExxonMobil Foundation [S18200000000256]

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The US Environmental Protection Agency's new rule, which considers sub-threshold responses for the first time, may impact global scientific research design and methodology, as well as regulatory actions in China and other countries.
With a rule published on 6 January 2021, the US Environmental Protection Agency (EPA) considers for the first time sub-threshold responses, abandoning the use of default dose-response models. This may affect worldwide scientific research, in terms of research design and methodology, and regulatory actions in China and other countries.

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