4.3 Review

Orchestrating multiplexity in polychromatic science through OMIPs: A decade-old resource to empower biomedical research

Journal

CYTOMETRY PART A
Volume 99, Issue 9, Pages 866-874

Publisher

WILEY
DOI: 10.1002/cyto.a.24471

Keywords

immune cells; multicolor flow cytometry; OMIP; panel design

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After ten years of development, the optimized multicolor immunofluorescence panel (OMIP) platform has evolved to cover larger panel sizes, increased number of subpopulations, and new species. This review summarizes the content and purpose of this collection for the research community, with the hope that readers will use these panels to enhance and expedite their research.
As the optimized multicolor immunofluorescence panel (OMIP) platform entered its 10th anniversary since its launch, the multicolor flow cytometry landscape has changed significantly. Likewise, OMIPs have continuously evolved to cover larger panel sizes, increasing number of subpopulations profiled in a single panel, and new species. After a decade of contributions to the OMIP platform, a review of this collection, summarizing its content and purpose for the research community, is timely and due. This review provides an overview of OMIPs and a presentation of the depth and diversity of this collection of validated panels, with the expectation that readers will take advantage of them to empower and accelerate their research.

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