Using Serum Biomarkers for Identifying Unstable Carotid Plaque: Update of Current Evidence

Carotid atherosclerosis is responsible for a great proportion of ischemic strokes. Early identification of unstable or vulnerable carotid plaques, and therefore, of patients at high risk for stroke, is of significant medical and socioeconomical value. We reviewed the current literature and discussed the potential role of the most important serum biomarkers in identifying patients with carotid atherosclerosis who are at high risk for atheroembolic stroke.

Automated summary

Carotid atherosclerosis is a major cause of ischemic strokes. Early identification of vulnerable carotid plaques is crucial for determining high-risk patients for stroke, and the potential role of serum biomarkers in this identification process is discussed in this review.