4.5 Article

The host glycomic response to pathogens

Journal

CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 68, Issue -, Pages 149-156

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2020.12.011

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Funding

  1. Canada Excellence Research Chairs Program

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Recent discoveries have shed light on the roles of glycans in infectious diseases, particularly in the host glycome response to infection. While the functions and dynamics of host glycans during infection are still not fully understood, new findings have provided insights into the mechanisms and implications of these interactions in host immunity.
Glycans play important roles in the biology of infectious diseases. Although glycans are expressed on both the pathogens and the host, the functions and dynamics of the host glycome during infection are not well understood. Recent years have witnessed new discoveries on the host glycome respsonse to infection, as well as related mechanisms and their implications. Herein, we present a brief review on the latest findings in this field and put them in the context of host immunity.

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