Journal
CURRENT OPINION IN ORGAN TRANSPLANTATION
Volume 26, Issue 4, Pages 412-418Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOT.0000000000000888
Keywords
COVID-19; outcomes; solid organ transplant; treatment; vaccine
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Funding
- National Institute of Allergy and Infectious Diseases of the National Institutes of Health [T32AI114398]
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The COVID-19 pandemic poses a major challenge to global health, especially among vulnerable populations. Studies on treatment and prevention specific to solid organ transplant recipients are urgently needed.
Purpose of review The COVID-19 pandemic is a major challenge to global health, particularly among vulnerable populations. Here, we describe the emerging epidemiology and relevant data on treatment options for COVID-19. We discuss the implications of current knowledge for solid organ transplant (SOT) recipients. Recent findings Risk factors and outcomes of COVID-19 among SOT recipients remain uncertain, but recent data suggest similar outcomes to the general population. Case reports of donor-derived SARS-CoV-2 infection are emerging. Few studies on treatment of COVID-19 among SOT recipients are available, and therefore, general recommendations are similar to the general population. Vaccine efficacy in the SOT population is uncertain. COVID-19 remains a significant threat to SOT recipients and studies on treatment and prevention specific to this population are urgently needed. Although vaccines represent the greatest hope to control this pandemic, their efficacy in this immunocompromised population is uncertain.
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