4.6 Review

Invasive pulmonary aspergillosis associated with viral pneumonitis

Related references

Note: Only part of the references are listed.
Letter Infectious Diseases

Invasive aspergillosis in patients with severe COVID-19 pneumonia

Marie Helleberg et al.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

Article Microbiology

COVID-19-Associated Invasive Aspergillosis: Data from the UK National Mycology Reference Laboratory

Andrew M. Borman et al.

Summary: Diagnosing CAPA poses challenges due to the lack of standardized algorithms and definitions, reluctance among clinicians to perform aerosol-generating bronchoalveolar lavages for testing, and uncertainty surrounding the diagnostic sensitivity of serum biomarkers. The study highlights the importance of a multimodal diagnostic approach involving regular and repeat testing of both serum and respiratory samples when diagnosing CAPA.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

Article Critical Care Medicine

Tissue-Specific Immunopathology in Fatal COVID-19

David A. Dorward et al.

Summary: In fatal COVID-19 cases, abnormal immune responses were found primarily in the lung and reticuloendothelial system, which were not clearly associated with the virus. Tissue-specific immunopathology in COVID-19 implicates a significant role of immune-mediated, virus-independent mechanisms in severe disease.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

Article Medicine, Research & Experimental

Alveolar epithelial cell type II as main target of SARS-CoV-2 virus and COVID-19 development via NF-Kb pathway deregulation: A physio-pathological theory

Maurizio Carcaterra et al.

Summary: The COVID-19 pandemic requires global collaborative efforts to define preventive and treatment strategies. One major challenge is the high number of patients requiring advanced respiratory support, with inflammation potentially playing a key role. Future therapeutic efforts may focus on targeting Type II alveolar cells to address the molecular pathogenic drivers associated with their dysfunction.

MEDICAL HYPOTHESES (2021)

Article Medicine, General & Internal

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia

Carlos Salama et al.

Summary: Among hospitalized patients with Covid-19 pneumonia not on mechanical ventilation, tocilizumab reduced the risk of progression to mechanical ventilation or death, but did not improve overall survival. There were no new safety concerns identified.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Medicine, General & Internal

Anakinra for patients with COVID-19: a meta-analysis of non-randomized cohort studies.

Laura Pasin et al.

Summary: Meta-analysis of studies on anakinra in COVID-19 patients suggests that its use may be associated with reduced mortality and need for mechanical ventilation, with no observed increase in adverse events. Further randomized clinical trials are needed to confirm these findings.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2021)

Article Immunology

IL-1 Receptor Antagonist Anakinra in the Treatment of COVID-19 Acute Respiratory Distress Syndrome: A Retrospective, Observational Study

Marco Franzetti et al.

Summary: The study found that the IL-1 receptor antagonist anakinra may be beneficial for patients with COVID-19-related ARDS, improving overall survival rates and reducing the need for invasive ventilation.

JOURNAL OF IMMUNOLOGY (2021)

Article Immunology

Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19

Nico A. F. Janssen et al.

Summary: The study conducted plasma cytokine measurements and proteomics analysis on 147 COVID-19 patients, uncovering a hyperinflammatory innate immune state and potential biomarkers. It revealed T-cell exhaustion in critically ill patients, with intact or hyperresponsive innate immune responses.

JOURNAL OF INFECTIOUS DISEASES (2021)

Article Infectious Diseases

Invasive pulmonary aspergillosis after treatment with tocilizumab in a patient with COVID-19 ARDS: a case report

Celeste Witting et al.

Summary: This case highlights the importance of considering opportunistic infections when providing immune modulating therapy.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2021)

Letter Critical Care Medicine

COVID-19-associated Pulmonary Aspergillosis

Andreas L. E. van Arkel et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)

Article Critical Care Medicine

Invasive Tracheobronchial Aspergillosis in Critically III Patients with Severe Influenza A Clinical Trial

Remy Nyga et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)

Letter Critical Care Medicine

COVID-19-associated invasive pulmonary aspergillosis

Lynn Rutsaert et al.

ANNALS OF INTENSIVE CARE (2020)

Letter Critical Care Medicine

Prevalence of putative invasive pulmonary aspergillosis in critically ill patients with COVID-19

Alexandre Alanio et al.

LANCET RESPIRATORY MEDICINE (2020)

Article Dermatology

COVID-19 associated pulmonary aspergillosis

Philipp Koehler et al.

MYCOSES (2020)

Letter Infectious Diseases

Incidence of invasive pulmonary aspergillosis among critically ill COVID-19 patients

Frederic Lamoth et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

Article Biotechnology & Applied Microbiology

COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis

Robert Lorenz Chua et al.

NATURE BIOTECHNOLOGY (2020)

Article Multidisciplinary Sciences

Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Raphael Cauchois et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Jerome Hadjadj et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

Donald J. Benton et al.

NATURE (2020)

Article Medicine, General & Internal

Efficacy of Tocilizumab in Patients Hospitalized with Covid-19

John H. Stone et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Multidisciplinary Sciences

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard et al.

SCIENCE (2020)

Article Critical Care Medicine

Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study

Emma J. Kooistra et al.

CRITICAL CARE (2020)

Article Rheumatology

Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study

Brandon J. Webb et al.

LANCET RHEUMATOLOGY (2020)

Article Immunology

Neutrophils Induce a Novel Chemokine Receptors Repertoire During Influenza Pneumonia

Jennifer M. Rudd et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2019)

Article Multidisciplinary Sciences

Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection

Benjamin M. Tang et al.

NATURE COMMUNICATIONS (2019)

Article Critical Care Medicine

Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study

Alexander F. A. D. Schauwvlieghe et al.

LANCET RESPIRATORY MEDICINE (2018)

Review Microbiology

Anti-Aspergillus Activities of the Respiratory Epithelium in Health and Disease

Margherita Bertuzzi et al.

JOURNAL OF FUNGI (2018)

Article Immunology

Invasive Aspergillosis Associated With Severe Influenza Infection

Nancy Crum-Cianflone

Open Forum Infectious Diseases (2017)

Article Immunology

Type III interferon is a critical regulator of innate antifungal immunity

Vanessa Espinosa et al.

SCIENCE IMMUNOLOGY (2017)

Letter Critical Care Medicine

Influenza-associated Aspergillosis in Critically III Patients

Frank L. van de Veerdonk et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)

Article Respiratory System

Influenza virus damages the alveolar barrier by disrupting epithelial cell tight junctions

Kirsty R. Short et al.

EUROPEAN RESPIRATORY JOURNAL (2016)

Editorial Material Cell Biology

Deficient autophagy unravels the ROS paradox in chronic granulomatous disease

Frank L. van de Veerdonk et al.

AUTOPHAGY (2014)

Review Biochemistry & Molecular Biology

Receptor binding and pH stability - How influenza A virus hemagglutinin affects host-specific virus infection

Caroline M. Mair et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)

Article Infectious Diseases

Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series

Corine E. Delsing et al.

BMC INFECTIOUS DISEASES (2014)

Review Biochemistry & Molecular Biology

Role of receptor binding specificity in influenza A virus transmission and pathogenesis

Miranda de Graaf et al.

EMBO JOURNAL (2014)

Article Medicine, General & Internal

Viral pneumonia

Olli Ruuskanen et al.

LANCET (2011)

Article Infectious Diseases

Invasive aspergillosis in chronic granulomatous disease

Brahm H. Segal et al.

MEDICAL MYCOLOGY (2009)

Article Immunology

Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages

O Ibrahim-Granet et al.

INFECTION AND IMMUNITY (2003)