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COVID-19 vaccines

Journal

CURRENT OPINION IN IMMUNOLOGY
Volume 71, Issue -, Pages 111-116

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2021.07.003

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Funding

  1. South African Medical Research Council [43500]

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The COVID-19 pandemic has led to significant advancements in vaccine development, with billions of doses administered worldwide by mid-2021. However, it is crucial to ensure equal access and optimal uptake of vaccines in all countries in order to bring an end to the pandemic.
COVID-19 is a pandemic of unprecedented proportions in recent human history. Less than 18 months since the onset of the pandemic, there are close to two hundred million confirmed cases and four million deaths worldwide. There have also been massive efforts geared towards finding safe and effective vaccines. By July 2021 there were 184 COVID-19 vaccine candidates in pre-clinical development, 105 in clinical development, and 18 vaccines approved for emergency use by at least one regulatory authority. These vaccines include whole virus live attenuated or inactivated, protein-based, viral vector, and nucleic acid vaccines. By mid-2021 three billion doses of COVID-19 vaccine have been administered around the world, mostly in high-income countries. COVID-19 vaccination provides hope for an end to the pandemic, if and only if there would be equal access and optimal uptake in all countries around the world.

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