DUXAP8: A Promising lncRNA with Carcinogenic Potential in Cancer

Background: Long non-coding RNAs (lncRNA) have influenced numerous biology processes, which has provoked great interest. Not only that, LncRNA DUXAP8 mediates tumorigenesis by affecting the activity of miRNAs, signaling pathways, and oncogene. Methods: The functions of DUXAP8 have been summarized by reading relevant articles on PubMed. Results: lncRNA DUXAP8 acts as an oncogene in most tumors. The abnormal over-expression is associated with the proliferation, invasion, migration, and anti-autophagy of tumors. DUXAP8 exerts promotion on Akt / mTOR signaling pathway, facilitating the occurrence of tumors. Furthermore, DUXAP8 affects the activity of miRNAs and proteins, showing its significant potential as a therapeutic target in human cancers. Conclusion: LncRNA DUXAP8 has been identified as an indispensable therapeutic target of the tumors, providing clinical treatment plans.

Automated summary

This article summarizes the role of lncRNA DUXAP8 in the occurrence and progression of tumors. It is found that DUXAP8 regulates the growth, invasion, and metastasis of tumors by affecting the activity of miRNAs, signaling pathways, and proteins. The research results suggest that DUXAP8 may be a potential therapeutic target for treating tumors.