Journal
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Volume 163, Issue -, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.critrevonc.2021.103371
Keywords
Exercise; Resistance training; Muscle hypertrophy; Lean body mass; Sarcopenia; Cancer
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Funding
- Deutscher Akademischer Austausch Dienst (DAAD)
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Resistance training can effectively counteract muscle loss in cancer patients, with better results in a supervised setting.
Background: Muscle wasting has a negative effect on treatment toxicity and cancer prognosis. Resistance training appears to be a promising approach to counteract the loss of muscle mass. Methods: Pubmed, Cochrane Library, SportDiscus and CINAHL. Randomized controlled resistance training trials with cancer survivros where eligible if lean body mass (LBM) or muscle mass were assessed. Results: A total of 34 trials were included into the primary analysis. Compared to the control individuals, the intervention groups show a superiority in LBM of 0.85 kg (95 % CI = 0.26-1.43, p = .004). Isolated, the participants in the intervention groups show an increase in LBM of 0.51 kg (95 % CI = - 0.05-1.06, p = .072); the control groups displayed a decrease of -0.59 kg (95 % CI= -1.04 to 0.06, p = .078). Supervision displayed an mediating role. Conclusions: Resistance training can counteract the loss of muscle mass in cancer patients. Especially in a supervised setting.
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