Journal
EXPERT REVIEWS IN MOLECULAR MEDICINE
Volume 18, Issue -, Pages -Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/erm.2016.2
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The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4/5/6 are implicated in development and differentiation of endoderm-and mesoderm-derived tissues such as induction of differentiation of embryonic stem cells, cardiovascular embryogenesis and guidance of epithelial cell differentiation in the adult.
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