Journal
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
Volume 25, Issue 7, Pages 1181-1186Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1386207324666210813121431
Keywords
Oxalis corniculata; anti-cancer; anti-diabetic; anti-oxidant; anti-fugal; anti-bacterial
Funding
- The Nagai Foundation Tokyo, Japan [NFT-R-2018]
- TWAS-COMSTECH Research Grant [17-180 RG/PHA/AS_C]
- NRPU Research Grants [8381/Punjab/NRPU/RD/HEC/2017, 8382/Punjab/NRPU/RD/HEC/20 17]
- International Foundation for Science [1I3_F_041125]
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Oxalis corniculata is a medicinal herb that grows in warm temperate and tropical regions. It has various bioactive compounds that have shown protective effects and biological activities. Despite its recognized usage, there is a lack of clinical trials and comprehensive pharmacological studies. However, this plant species has the potential for treating various diseases and further research is needed to explore its pharmacological applications.
Oxalis corniculata (Oxalidaceae) is a small decumbent and delicate appearing medicinal herb flourishing in warm temperate and tropical domains such as Pakistan and India. Main bioactive chemical constituents of Oxalis plant include several alkaloids, flavonoids, terpenoids, cardiac glycosides, saponins, and phlobatannins, along with steroids. Due to its polyphenolic, glycosides and flavonoid profile, it is proved to be protective in numerous ailments and exhibit various biological activities such as anti-fungal, anti-cancer, anti-oxidant, anti-bacterial, anti-diabetic, and cardioprotective. Moreover, bioactive phytochemicals from this plant possess significant wound healing potential. Our current effort intends to emphasize on the immense significance of this plant species, which have not been the subject matter of clinical trials and effective pharmacological studies, even though its favored usage has been stated. This review proposes that Oxalis corniculata possess a potential for the cure of various diseases. However, further researches on isolation and characterization of bioactive compounds along with pre-clinical trials are compulsory to figure out its pharmacological applications.
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