Bioinspired self-assembled nanoparticles with stable fluorescent properties in wide visible light region

Development of fluorescent materials with high photostability and biocompatibility is of great importance in biolabeling and bio-imaging. Herein, we employ amphiphilic amino acids as basic building blocks to fabricate stable biology self-luminous nanoparticles with a uniform size distribution of 300 nm. The endogenous property of amino acids endows the nanoparticles with high biocompatibility. More importantly, the nanoparticles can hold the property of multiple fluorescence emission in a wide wavelength range of 400-670 nm with high photostability. The dynamic fluorescence shift is as high as 1.36779. These properties make the nanoparticles a potential candidate for broad biomedical applications.

Automated summary

This study fabricated stable self-luminous nanoparticles using amphiphilic amino acids, which possess high biocompatibility and photostability. These nanoparticles exhibit multiple fluorescence emission in a wide wavelength range and have a high dynamic fluorescence shift, making them potential candidates for a broad range of biomedical applications.