4.7 Article

Opening of the Blood-Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models

Related references

Note: Only part of the references are listed.
Review Oncology

Blood-brain barrier opening with low intensity pulsed ultrasound for immune modulation and immune therapeutic delivery to CNS tumors

Kevin Beccaria et al.

Summary: Pulsed low intensity ultrasound has been developed as a safe technique to open the blood-brain barrier (BBB) and enhance the delivery of immune therapeutics to the brain, showing promising results in preclinical and clinical studies for brain tumor treatment. Ultrasound-induced BBB disruption not only controls tumor growth but also stimulates immune responses.

JOURNAL OF NEURO-ONCOLOGY (2021)

Article Oncology

MR-guided focused ultrasound liquid biopsy enriches circulating biomarkers in patients with brain tumors

Ying Meng et al.

Summary: This study demonstrates that MRgFUS has the potential to enrich circulating brain-derived biomarkers, showing promising applications for liquid biopsy in the brain.

NEURO-ONCOLOGY (2021)

Article Multidisciplinary Sciences

Noninvasive hippocampal blood-brain barrier opening in Alzheimer's disease with focused ultrasound

Ali R. Rezai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Feasibility and safety of focused ultrasound-enabled liquid biopsy in the brain of a porcine model

Christopher Pham Pacia et al.

SCIENTIFIC REPORTS (2020)

Article Medicine, Research & Experimental

Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target

Jun Wei et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Article Oncology

T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma

Karolina Woroniecka et al.

CLINICAL CANCER RESEARCH (2018)

Article Biochemistry & Molecular Biology

Chemokines beyond chemo-attraction: CXCL10 and its significant role in cancer and autoimmunity

Nathan Karin et al.

CYTOKINE (2018)

Review Medicine, Research & Experimental

CXCL9, CXCL10, CXCL11, and their receptor (CXCR3) in neuroinflammation and neurodegeneration

Olga M. Koper et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2018)

Article Multidisciplinary Sciences

Focused Ultrasound-enabled Brain Tumor Liquid Biopsy

Lifei Zhu et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

Pakawat Chongsathidkiet et al.

NATURE MEDICINE (2018)

Review Biochemistry & Molecular Biology

CD4 and CD8 T lymphocyte interplay in controlling tumor growth

Dmitrij Ostroumov et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Oncology

Migrating into the Tumor: a Roadmap for T Cells

Lieke L. van der Woude et al.

TRENDS IN CANCER (2017)

Article Medicine, Research & Experimental

CD19 CAR-T cells of defined CD4+: CD8+ composition in adult B cell ALL patients

Cameron J. Turtle et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Radiology, Nuclear Medicine & Medical Imaging

Focused Ultrasound Enhances Central Nervous System Delivery of Bevacizumab for Malignant Glioma Treatment

Hao-Li Liu et al.

RADIOLOGY (2016)

Article Cell Biology

Clinical trial of blood-brain barrier disruption by pulsed ultrasound

Alexandre Carpentier et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients

Duane A. Mitchell et al.

NATURE (2015)

Article Multidisciplinary Sciences

Structural and functional features of central nervous system lymphatic vessels

Antoine Louveau et al.

NATURE (2015)

Editorial Material Clinical Neurology

Focused Ultrasound With Microbubbles Increases Temozolomide Delivery in U87 Transfected Mice

Christopher P. Deibert et al.

NEUROSURGERY (2015)

Article Endocrinology & Metabolism

The size of blood-brain barrier opening induced by focused ultrasound is dictated by the acoustic pressure

Hong Chen et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)

Article Chemistry, Multidisciplinary

Prolonged survival upon ultrasound-enhanced doxorubicin delivery in two syngenic glioblastoma mouse models

Zsofia Kovacs et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Article Immunology

Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection

Johannes vom Berg et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2013)

Article Endocrinology & Metabolism

Dynamic study of blood-brain barrier closure after its disruption using ultrasound: a quantitative analysis

Benjamin Marty et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)

Review Immunology

T cell exhaustion

E. John Wherry

NATURE IMMUNOLOGY (2011)

Editorial Material Clinical Neurology

Vaccine provides new hope for patients with deadly brain cancer

[Anonymous]

FUTURE NEUROLOGY (2010)

Article Oncology

Noninvasive detection of therapeutic cytolytic T cells with F-18-FHBG PET in a patient with glioma

Shahriar S. Yaghoubi et al.

NATURE CLINICAL PRACTICE ONCOLOGY (2009)

Article Multidisciplinary Sciences

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption

Manabu Kinoshita et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Immunology

Activation of dendritic cells via inhibition of Jak2/STAT3 signaling

Y Nefedova et al.

JOURNAL OF IMMUNOLOGY (2005)

Article Radiology, Nuclear Medicine & Medical Imaging

Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits

K Hynynen et al.

RADIOLOGY (2001)