Standardized Uptake Value Illuminates Tumor Inflammation and Treatment Response

Maximum standardized uptake value (SUVmax) on PET imaging is prognostic in cervical cancer. It was recently demonstrated that low pretreatment SUVmax is associated with superior prognosis and is correlated with decreased inflammatory signaling and myeloid-derived cell infiltration into the tumor microenvironment, potentially identifying susceptibility to targeted therapies.

Automated summary

In cervical cancer, PET imaging with maximum standardized uptake value (SUVmax) has prognostic significance. Low pretreatment SUVmax is associated with a better prognosis and correlated with decreased inflammatory signaling and myeloid-derived cell infiltration, potentially indicating susceptibility to targeted therapies.