Emerging 2D pnictogens for biomedical applications

Two-dimensional (2D) materials composed of single pnictogen element, namely, 2D pnictogens (e.g., black phosphorus, arsenene, antimonene and bismuthine), have recently showed remarkable potential for biomedical applications, especially after the rapid development of black phosphorus. With unique optical and electronic properties, 2D pnictogens are considered as promising nanoagents for biosensors, diagnosis and therapy. In this review, after brief introduction of the structure, properties, synthesis strategies, and biocompatibility of 2D pnictogens, their biomedical applications including anti-tumor, anti-inflammation, anti-bacterial, neurodegenerative treatment and tissue repairing are reviewed. The major obstacles and opportunities of 2D pnictogens are also discussed. This review provides a short yet timely summary on the synthesis and biomedical applications of emerging 2D pnictogens. (C) 2021 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

Automated summary

This review summarizes the synthesis and biomedical applications of two-dimensional pnictogens, including biosensors, diagnosis, and therapy. It provides an overview of the structure, properties, synthesis strategies, and biocompatibility of these materials, as well as their applications in various biomedical fields. The major challenges and opportunities of two-dimensional pnictogens are also discussed.