4.1 Article

Monofunctionalized Gold Nanoparticles: Fabrication and Applications

Journal

CHIMIA
Volume 75, Issue 5, Pages 414-426

Publisher

SWISS CHEMICAL SOC
DOI: 10.2533/chimia.2021.414

Keywords

Gold Nanoparticle; Labeling; Monofunctional; Plasmonics; Superstructure

Funding

  1. Swiss National Science Foundation [200020_178808]
  2. 111 project [90002-18011002]
  3. Swiss National Science Foundation (SNF) [200020_178808] Funding Source: Swiss National Science Foundation (SNF)

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This review provides an overview of various approaches to synthesize gold nanoparticles (AuNPs) with a single chemically addressable unit and their diverse fields of application. The complementary physical properties of AuNPs combined with precise chemical control of their attachment make them promising building blocks for numerous proof-of-concept experiments and applications.
An overview of various approaches to synthesize gold nanoparticles (AuNPs) bearing one single chemically addressable unit and their diverse fields of application is presented. This comprehensive review not only describes the strategies pursued to obtain monofunctionalized AuNPs, but also reports their behavior as 'massive' molecules in wet chemical protocols and the scope of their applications. The latter reaches from site-specific labels in biomolecules over mechanical barriers in superstructures to building blocks in hybrid nano-architectures. The complementing physical properties of AuNPs combined with precise chemical control of their attachment makes these objects promising building blocks for numerous proof-of-concept experiments and applications.

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