Journal
EXPERT OPINION ON DRUG SAFETY
Volume 15, Issue 4, Pages 457-465Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1517/14740338.2016.1140743
Keywords
glucocorticoids; immunosuppression; side effects; corticosteroids
Categories
Funding
- Alcon
- Aldeyra Therapeutics
- Bausch Lomb
- Clearside Biomedical
- Dompe Pharmaceutical
- Eyegate Pharma
- Icon
- Novartis
- pSivida
- Santen
- Xoma
- Allergan
- Scientific and Technological Research Council of Turkey
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Introduction: Glucocorticoids represent the standard therapy for reducing inflammation and immune activation in various diseases. However, as with any potent medication, they are not without side effects. Glucocorticoid-associated side effects may involve most major organ systems. Musculoskeletal, gastrointestinal, cardiovascular, endocrine, neuropsychiatric, dermatologic, ocular, and immunologic side effects are all possible.Areas Covered: This article analyzes English-language literature and provides an update on the most recent literature regarding side effects of systemic glucocorticoid treatment.Expert Opinion: The risk/benefit ratio of glucocorticoid therapy can be improved by proper use. Careful monitoring and using appropriate preventive strategies can potentially minimize side effects.
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